Protein Alignment ACXD and Gucy1b1

DIOPT Version :9

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_059497.1
• Gene: Gucy1b1 / 54195
• MGIID: 1860604
• Length: 620
• Species: Mus musculus
• Alignment Length: 489
• Identity: 108/489 - (22%)
• Similarity: 195/489 - (39%)
• Gaps: 124/489 - (25%)

  Fly    79 HTLLLLTTPEIKY--VYVDMVAY--------------MCSGLVIWVVLGVNFRSELVSKHGWVVY 127
            ||..|:...|.|.  .|.|:..:              .|......::..   |:.:|::.|..:|
Mouse   176 HTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFD---RNLVVTQCGNAIY 237

  Fly   128 AT---------SWLAVCVMVLMDIGLNVYHATSHNDILNPIYDAYTLYAIYMFMPVPYLLQPFVL 183
            ..         |.|:|..:|...|.:      |.:.||:.|...:.|.:....:.|..|.....|
Mouse   238 RVLPQLQPGNCSLLSVFSLVRPHIDI------SFHGILSHINTVFVLRSKEGLLDVEKLECEDEL 296

  Fly   184 GSAVTFCYIINYSFVITAKDDNQMH----SILN------EAIYLSCVN---------LLGIFFR- 228
            ..|...|..:....:...:.|:.:.    |::|      ..:|||.:.         |||..||
Mouse   297 TGAEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFRE 361

  Fly   229 ---LMRDIALRTTFLDRRQYVEENLLLRYARDQER---SLLLSILPAQIADRLQEDVKNRIERSK 287
               |.:::.:.|   ||.|     |.||...|:::   :||.|:||..:|:.|
Mouse   362 EYKLTQELEILT---DRLQ-----LTLRALEDEKKKTDTLLYSVLPPSVANEL------------ 406

  Fly   288 QQHQQQSQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYT-----HLTTTLDVKK 347
             :|::  .|..:|                      :::||:|::.:|.:.     |.:.. ...|
Mouse   407 -RHKR--PVPAKR----------------------YDNVTILFSGIVGFNAFCSKHASGE-GAMK 445

  Fly   348 LVEALHDLFVRFDIASEEYN---VLRIKFLGDCYYCVAGLANPNADHAKCCVDLGLRMIKDIRDV 409
            :|..|:||:.|||..::...   |.:::.:||.|..|:||..|...||:....|.|.|::....|
Mouse   446 IVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQV 510

  Fly   410 REKRHLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSLLDG 474
            :.... ::.:.||:|:|:|::||||....::.::...|::.:|.|.||..|:::||
Mouse   511 QVDGE-SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVS--------- 565

  Fly   475 EYFFEDGTEKAREDPVLQKHGIRTFLIKSLRAPM 508
            ||.:.........||:..........:|..:.||
Mouse   566 EYTYRCLMSPENSDPLFHLEHRGPVSMKGKKEPM 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831	54/255 (21%)
		CYCc	254..476	CDD:214485	55/232 (24%)
		Nucleotidyl_cyc_III	321..503	CDD:299850	48/189 (25%)
		CYCc	856..1117	CDD:214485
		Nucleotidyl_cyc_III	878..1142	CDD:299850
Gucy1b1	NP_059497.1	HNOB	2..166	CDD:311572
		HNOBA	207..406	CDD:311573	46/215 (21%)
		Guanylate_cyc	412..605	CDD:306677	53/221 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900