Protein Alignment ACXD and ACXA

DIOPT Version :10

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_620475.2
• Gene: ACXA / 53432
• FlyBaseID: FBgn0040510
• Length: 1112
• Species: Drosophila melanogaster
• Alignment Length: 1169
• Identity: 452/1169 - (38%)
• Similarity: 660/1169 - (56%)
• Gaps: 130/1169 - (11%)

  Fly    31 NEKNWEWSYLVRKCRNLELEDSYDLYMRRLRVGYLSLFI-FIHVAVTVIHTLLLLTTPEIKYVYV 94
            ||:.||.|||..:|:.|.||:.|..|..||.:..|::|: .:.:.:..:..::...|...||:|:
  Fly    24 NERLWEQSYLKARCKELHLEEEYMKYKIRLMISSLTVFVPMLILLIVALQVIIWSFTEYTKYIYI 88

  Fly    95 DMVAYMCSGLVIWVVLGVNFRSELVSKHGWVVYATSWLAVCVMVLMDIGLNVYHATSHNDILNPI 159
            :.:..:.|.:::..:|.:||..:.|.:|.||:..||.|:..|:||.||..|.|:....|..||.:
  Fly    89 NAIFDLGSLILVTGLLSINFFEDFVIRHRWVMTFTSTLSAYVVVLGDIAFNTYYYYKSNWPLNTL 153

  Fly   160 YDAYTLYAIYMFMPVPYLLQPFVLGSAVTFCYIINYSFVITAKDDN---QMHSILNEAI----YL 217
            ||.:.|..||||:|:|......:|..:|:..|:|.:...:...:.|   .:|.:...:|    ||
  Fly   154 YDVFVLCMIYMFLPIPSSKAAALLAISVSLTYVIYFIHFMAFNEHNVAKYVHGLDIVSIDFFHYL 218

  Fly   218 SCVNLLGIFFRLMRDIALRTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIADRLQEDVKNR 282
            . .|::|||||:|.|..:|::||||.|::.|.:.||.||.||..||.||||.|||..:|:.:|.:
  Fly   219 G-FNMMGIFFRIMNDTMVRSSFLDRYQFITEEIWLRQARRQESLLLDSILPPQIAKPIQKSIKEK 282

  Fly   283 IERSKQQHQQQSQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTHLTTTLDVKK 347
            |        .|...|......|:|.:.:       :.|:.|.||::||||:||||.|||||.|:|
  Fly   283 I--------IQPDNDFYHLGTSRTAENF-------MSIQIHNDVSILYADLVNYTQLTTTLTVEK 332

  Fly   348 LVEALHDLFVRFDIASEEYNVLRIKFLGDCYYCVAGLANPNADHAKCCVDLGLRMIKDIRDVREK 412
            ||:.||||:.|||:|:..:.|.|||||||||||||||...:.|||...|.||:.||.:|::|...
  Fly   333 LVKVLHDLYARFDLAALSFKVQRIKFLGDCYYCVAGLGESDPDHATMAVSLGISMIANIKEVSVN 397

  Fly   413 RHLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSLLDG-EY 476
            |.|||.||||||||.:.:||||.||.|:|||..||:||:||||||:.|.||||.:|||.|:. ||
  Fly   398 RSLNIGMRIGVHSGTLFAGVIGKAKLQYDIWGADVNIASRLEATGSPGYVHVSGRTLSSLNAEEY 462

  Fly   477 FFEDGTEKAREDPVLQKHGIRTFLIKSLRAPMHD---------PRRRMRERQVKKLSEASKANFM 532
            ....|||.|::|||||||.:.|:|:.::.:...|         |...::.....:.|:..|.|.:
  Fly   463 NIYPGTESAQKDPVLQKHPMSTYLLTAIPSLDSDKTISIVEGVPNLDLQTVGSNRKSQILKPNLL 527

  Fly   533 HNSTLHQYNQVRNQAKLEMCRELDKMPIGRIQLTKVFRRSTRLTQDEIEEETFRRNISSCCLFFR 597
            .:               ||..|..|||:|..:....:.|..|    .::.|...|::...|:.|:
  Fly   528 SH---------------EMREEFRKMPVGGFKFQFPWSRRER----NLKNEKVERDLGIFCVAFK 573

  Fly   598 IRNWEFQYIKEPDVMLKYSIALAWVIYMGLLTIQLL-SKDARYHYWYIDGTTIILLTMLLIVSWY 661
            .::.|:.|:.:||.:.|||:||.|.|...|:.||.: :.|..|....|:.....:||.||.:.||
  Fly   574 DKSVEWNYLHQPDYIFKYSVALGWGIGCCLIYIQSVNNSDIFYTGVVINIIAFFVLTFLLFICWY 638

  Fly   662 KKL-WIMYMSDADVSSPNGRLSGFLFRMSDEMQRNVVIRVVMYFLIIFSYCAVAIMQVVGCSSDE 725
            ||: |  :.|..:.....|:||..:|.:.:::|.:.|:|:.:|.:||..|..|..:.::.|..|:
  Fly   639 KKVCW--WHSGQNEHRSYGKLSCAIFHLFEKIQHSFVLRLTVYMMIILCYYMVISLILMSCEKDQ 701

  Fly   726 -----------DYADLDPTYDERVQCFHPWILTNCMTLVIGMSFLFTRIPFIIKSCFSALIMIGY 779
                       :| |:||     ..|||||..||.|.|::|||:.|.||||.:|:.......:.:
  Fly   702 YELDIIESKLYNY-DMDP-----FTCFHPWAYTNMMALILGMSYTFARIPFALKTFIGCAEAVVF 760

  Fly   780 AVLVVSEFNFIYANSPSTNVNFNAKYSH---ILLMIITFGIFHLMERQTEFIAKVDYNWKRQLIK 841
            .::|..::.||:.:|.:|:....|:.:|   :.:|:||   .:..|||:||..|::|.....|..
  Fly   761 VLVVCFQYAFIFEHSVTTSPYLKAEIAHSCRVCMMLIT---MYAKERQSEFNTKMNYKLNLDLQN 822

  Fly   842 KQEDALITNDTIKVLLTNILPTHVADFYLSNQLQNELYYEEYDNVAVMFASIKNFDTDKIGLRVL 906
            ||:.|.:||.:|.:||.||||:||.:.|||:..::|||||.|..|:||||.:.||..|...||||
  Fly   823 KQKSADVTNQSIIILLNNILPSHVVEVYLSSIAKHELYYENYRMVSVMFAMLTNFQMDLPSLRVL 887

  Fly   907 NEIICDFDDVLNKYSQSLRVEKIKVANWTYMAACGLDVSRSEQVNAPQMKFRNVSLMPNGRRSRY 971
            |:||..||.:|:.|.|...||||||...|||||||||.|..|.::
  Fly   888 NDIITAFDRLLSAYKQYYVVEKIKVVGCTYMAACGLDFSLIENLD-------------------- 932

  Fly   972 DGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVITSGPRISSTHNGSSSNEVVRVMAEFAL 1036
                 ||:         |..:.:|..:||:.:         .|:.|:....:.:||..:||.|||
  Fly   933 -----SNS---------NFGSTSLSSELEQVR---------SRLESSIKEKNHDEVAFIMATFAL 974

  Fly  1037 DLMRTMRRFNTENMQTEYEGSTDYGMLRIGISHGRAMAGVVGISKPHYDIWGNPVNMASRMDSTG 1101
            ||||.:...|.......::.:...|.:|||||.|:.||||||.|:||||||||||||||||:|||
  Fly   975 DLMRVLSVCNKAYAGEPFDRALSTGEIRIGISTGQIMAGVVGASQPHYDIWGNPVNMASRMESTG 1039

  Fly  1102 VPGQIQVTENTALKLREFNIQCNYRGMTFVKGRGNIPTYIIGIDSEYQF-------LPHRPAAP 1158
            :.|.||||:.||..|.||::.|.|||:|||||||.||||.:|||.:.:|       |...|:.|
  Fly  1040 LSGHIQVTKETAQTLEEFDVMCYYRGLTFVKGRGEIPTYFVGIDKDLKFMSKKIDRLSENPSNP 1103

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:318454	85/249 (34%)
		Nucleotidyl_cyc_III	321..503	CDD:448371	110/182 (60%)
		Nucleotidyl_cyc_III	878..1142	CDD:448371	120/263 (46%)
ACXA	NP_620475.2	AcyC	88..457	CDD:441717	171/384 (45%)
		Nucleotidyl_cyc_III	306..489	CDD:448371	110/182 (60%)
		Nucleotidyl_cyc_III	859..1080	CDD:448371	120/263 (46%)