Protein Alignment ACXD and ACXE

DIOPT Version :10

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Alignment Length: 1166
• Identity: 457/1166 - (39%)
• Similarity: 663/1166 - (56%)
• Gaps: 140/1166 - (12%)

  Fly    32 EKNWEWSYLVRKCRNLELEDSYDLYMRRLRVGYLSLFIFIHVAVTVIHTLLLLTTPEIK-YVYVD 95
            |:.||..||..||..|.||..:.||..||...||..|..:|:.||.:|..|||.|.|.: .:|.|
  Fly    15 ERMWEPGYLKAKCAELRLESEFRLYRIRLWKSYLLTFFMLHIFVTSVHCALLLATIERRSIIYFD 79

  Fly    96 MVAYMCSGLVIWVVLGVNFRSELVSKHGWVVYATSWLAVCVMVLMDIGLNVYHATSHNDILNPIY 160
            :...:...||:.:||.|||..|.::||.|.:||:|..|...:|..|:..::||..:|:.||...|
  Fly    80 VALSIGCALVLILVLSVNFCDEFIAKHTWYMYASSIFASLTLVFADLTESIYHTYAHSWILGTFY 144

  Fly   161 DAYTLYAIYMFMPVPYLLQPFVLGSAVTFCYIINYSFVITAKDDNQMHSIL-------NEAIYLS 218
            |.|.:|.||||:|:.::....:|...|:..||: |..:..|:...|..|.|       .:.::..
  Fly   145 DTYIIYMIYMFLPIHFISGAVLLALLVSGLYIL-YFVIFIAQGFAQFASALFSVGGMSVDIVHYL 208

  Fly   219 CVNLLGIFFRLMRDIALRTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIADRLQEDVKNRI 283
            |:||:|||:|:|.|..:|::||||.||::|.:.||.||.||:.||.||||.||:..||:|::.||
  Fly   209 CLNLVGIFYRVMNDTVVRSSFLDRHQYIKEKIWLRNARLQEKQLLDSILPPQISLPLQKDIQGRI 273

  Fly   284 ERSKQQHQQQSQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTHLTTTLDVKKL 348
            ..:|                 |.:..|...:. |:.|:.|.||::|||||||||||||||.|:.|
  Fly   274 VMAK-----------------QGIHSWTAMER-TMAIQIHPDVSILYADVVNYTHLTTTLTVEML 320

  Fly   349 VEALHDLFVRFDIASEEYNVLRIKFLGDCYYCVAGLANPNADHAKCCVDLGLRMIKDIRDVREKR 413
            |:.||||:.|||:|:..|.|.|||||||||||||||::|:.|||..||.|||.||..|.:||:..
  Fly   321 VKVLHDLYGRFDLAAYRYKVQRIKFLGDCYYCVAGLSDPDPDHANNCVILGLSMINHIMEVRDIH 385

  Fly   414 HLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSLLDGEYF- 477
            .|:|:||||||||::.:||||.||.|||||..||.|||.||:||..|.||:|..||:.||...|
  Fly   386 GLDINMRIGVHSGNLFAGVIGEAKLQFDIWGLDVTIANVLESTGVPGCVHISGATLNNLDVNRFD 450

  Fly   478 FEDGTEKAREDPVLQKHGIRTFLIKSLRAPMHDPRRRMRERQVKKLSEASKANF---MHNSTL-- 537
            .|||.|:||:.|:|:|:.||:::|                ||...:.:.....|   :|:.:|
  Fly   451 IEDGPEEARDHPLLKKYRIRSYII----------------RQDLHMDDEDSDEFLGDLHSISLCN 499

  Fly   538 --------HQYNQ-VRNQAKLEMCRELDKMPIGRI---QLTKVFRRSTRLTQDEIEEETFRRNIS 590
                    ...|| :|.....|:..|..|||:...   :|..:.|.:|.      :|....:|:
  Fly   500 MGAQPRISDSANQSLRALFHEELREEFRKMPVSAFSPKRLLGICRFNTG------KEVPAHQNL- 557

  Fly   591 SCCLFFRIRNWEFQYIKEPDVMLKYSIALA-----WVIYMGLLTIQLLSKDARYHYWYIDGTTII 650
            :.||.|.....|..|:|:.|.|.||||.|:     .::|:.|:..|::....    :.:..:...
  Fly   558 NICLTFTDPILERAYLKQTDYMYKYSIILSASVGCSLVYIELMDTQMICSSC----FVLPASVAT 618

  Fly   651 LLTMLLIVSWYKK-LWIMYMSDADVSSPNGRLSGFLFRMSDEMQRNVVIRVVMYFLIIFSYCAVA 714
            :..:|.:::|||| .|..|..:......|| .|.|:||:.|::..::.||:.:|..::.|...|.
  Fly   619 IQCILALIAWYKKYCWTRYGRNNVPHHYNG-FSCFIFRIHDKILNSLPIRICIYLFLMISSFFVM 682

  Fly   715 IMQVVGCSSDE-DYADLDPT---YDERVQ-CFHPWILTNCMTLVIGMSFLFTRIPFIIKSCFSAL 774
            .:.|:.|..:| :.|.::..   |::... |||||:.||.::|:|.::|.|..||.::|:..:.|
  Fly   683 CLIVMSCQREEFEMAYIEERLFHYEQEAHICFHPWVTTNMLSLMICLTFTFAHIPIMVKTAVAIL 747

  Fly   775 IMIGYAVLVVSEFNFIYANSPSTNVNFNAKYSHILLMIITFGIFHLMERQTEFIAKVDYNWKRQL 839
            ..:.|.:|:..:|:|::.:|.:||..|.::|:|.||:.|||.|..:.|||.||..||::||:..|
  Fly   748 ETLAYLLLIFFQFDFVFHHSVTTNPYFKSEYAHALLICITFLIMFVKERQIEFTNKVNFNWRVDL 812

  Fly   840 IKKQEDALITNDTIKVLLTNILPTHVADFYLSNQLQNELYYEEYDNVAVMFASIKNFDTDKIGLR 904
            .|::..|.:||.:|.::|.||||:|:.|.||::..::|||:|.|..|:||||.:.||:.|...||
  Fly   813 RKEENAASLTNHSIIIILNNILPSHIVDVYLNSLAKHELYFENYRMVSVMFAMLINFEMDLRSLR 877

  Fly   905 VLNEIICDFDDVLNKYSQSLRVEKIKVANWTYMAACGLDV------SRSEQVNAPQMKFRNVSLM 963
            ||||||.:||.:|..|.:...|||||:...|||||||||:      |.:.:.:.|..:|
  Fly   878 VLNEIIAEFDTLLLFYKEYYTVEKIKIVGCTYMAACGLDLNFAGSTSTNRKESIPPTEF------ 936

  Fly   964 PNGRRSRYDGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVITSGPRISSTHNGSSSNEVV 1028
             |..:||....:.||.                |||                           |||
  Fly   937 -NEEQSRRILFQQSNE----------------DLD---------------------------EVV 957

  Fly  1029 RVMAEFALDLMRTMRRFNTENMQTEYEGSTDYGMLRIGISHGRAMAGVVGISKPHYDIWGNPVNM 1093
            .||..:|||:|||:.:.|........:.:...|.:.||||.|..|||:||.|:||||||||||||
  Fly   958 FVMTSYALDMMRTLAKSNEAYQSIAGDRNITDGTIAIGISSGEVMAGIVGASQPHYDIWGNPVNM 1022

  Fly  1094 ASRMDSTGVPGQIQVTENTALKLREFNIQCNYRGMTFVKGRGNIPTYIIGIDSEYQFLPHR 1154
            ||||:|||:||.|.|||.|:..|::|.|.|:|||||||||||.||||::|||....|:|.:
  Fly  1023 ASRMESTGLPGHIHVTEETSEILQQFGITCSYRGMTFVKGRGKIPTYLVGIDENLNFIPQK 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:318454	98/249 (39%)
		Nucleotidyl_cyc_III	321..503	CDD:448371	111/182 (61%)
		Nucleotidyl_cyc_III	878..1142	CDD:448371	118/269 (44%)
ACXE	NP_652601.3	AcyC	65..453	CDD:441717	187/406 (46%)
		Nucleotidyl_cyc_III	290..459	CDD:448371	104/168 (62%)
		Nucleotidyl_cyc_III	851..1071	CDD:448371	118/269 (44%)