DRSC/TRiP Functional Genomics Resources

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Protein Alignment ACXD and Gucy1a1

DIOPT Version :10

Sequence 1:NP_620469.2 Gene:ACXD / 38284 FlyBaseID:FBgn0040507 Length:1162 Species:Drosophila melanogaster
Sequence 2:NP_058786.2 Gene:Gucy1a1 / 497757 RGDID:68436 Length:690 Species:Rattus norvegicus


Alignment Length:349 Identity:79/349 - (22%)
Similarity:147/349 - (42%) Gaps:100/349 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   192 IINYSFVI-------TAKDDNQMHSILNEAIYL-----------SCVNLL------GIFF----- 227
            ::|..|||       ..|..:::..:..:.||:           .||:.|      |::.     
  Rat   340 MLNMQFVIRVRRWDNLVKKSSRVMDLKGQMIYIVESSAILFLGSPCVDRLEDFTGRGLYLSDIPI 404

  Fly   228 -RLMRDIA------------------LRTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIAD 273
             ..:||:.                  |:.|.....|.:||.      :.:...||.||.|:::|.
  Rat   405 HNALRDVVLIGEQARAQDGLKKRLGKLKATLEHAHQALEEE------KKKTVDLLCSIFPSEVAQ 463

  Fly   274 RLQEDVKNRIERSKQQHQQQSQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTH 338
            :|.:   .:|.::|:                                  ..:||:|::|:|.:|.
  Rat   464 QLWQ---GQIVQAKK----------------------------------FNEVTMLFSDIVGFTA 491

  Fly   339 LTTTLDVKKLVEALHDLFVRFDIASEEYNVLRIKFLGDCYYCVAGLANPNAD-HAKCCVDLGLRM 402
            :.:.....:::..|:.|:.|||....|.:|.:::.:||. |||||..:..:| ||.....:.|:|
  Rat   492 ICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDA-YCVAGGLHRESDTHAVQIALMALKM 555

  Fly   403 IKDIRDVREKRHLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQK 467
            ::...:|.......|.||||:|||.|.:||:|....::.::..:|.:||:.|:.....:::||..
  Rat   556 MELSNEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPT 620

  Fly   468 TLSLL---DGEYFFEDGTEKARED 488
            |..||   .|..|    |.::||:
  Rat   621 TYRLLKDCPGFVF----TPRSREE 640

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ACXDNP_620469.2 AC_N <42..284 CDD:318454 25/139 (18%)
Nucleotidyl_cyc_III 321..503 CDD:448371 52/172 (30%)
Nucleotidyl_cyc_III 878..1142 CDD:448371
Gucy1a1NP_058786.2 HNOBA 276..465 CDD:462234 24/130 (18%)
Guanylate_cyc 471..642 CDD:425528 53/209 (25%)
Blue background indicates that the domain is not in the aligned region.

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