Protein Alignment ACXD and Ac3

DIOPT Version :10

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: XP_061511365.1
• Gene: Ac3 / 4578014
• VectorBaseID: AGAMI1_012876
• Length: 1207
• Species: Anopheles gambiae
• Alignment Length: 1188
• Identity: 306/1188 - (25%)
• Similarity: 536/1188 - (45%)
• Gaps: 259/1188 - (21%)

  Fly    49 LEDSYDLY-MRRLRVGYLSLFIFIHVAVTVIHTLLLLTTPE---IKYVYVDMVAYMCSGLVIWVV 109
            |:..|..| :::.||.:....|     .:::..:..:..|:   ::.:.|..| ::...:|:.:|
Mosquito    26 LDKLYQSYALKQKRVAFACYLI-----ASILFDVWAIAVPQGQSVESIVVTSV-FLTINIVLAIV 84

  Fly   110 LGV----NFRSEL--VSKHGWVVYATSWLAVCVMVLMDIGLNVYHATSHNDILNPIYDAYTLYAI 168
            |..    .||..:  ::.|      .:||.....:.:.:.|.  .:.:..|.|.  :.....:.:
Mosquito    85 LRFCGRGRFRGVIWEIAPH------LAWLLAIKQLFLQLFLK--GSVTPRDSLG--WAVLLNFLV 139

  Fly   169 YMFMPVPYLLQPFVLGSAVTFCYIINYSFVITAKDDN-----QMHSILNEAIYLSCVNLLGIFFR 228
            |:.:||.......:||.. :|...:| :.:..||.:|     |:.:||    .|....|:|:...
Mosquito   140 YVTLPVLLKYTGILLGLG-SFATYVN-AIIGLAKKENYFWEQQVANIL----LLIAATLIGLLCY 198

  Fly   229 LMRDIALRTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIADRLQEDVKNRIERSKQQHQQQ 293
            .:.:...|..||:.:|.:|..:|:.....::..||||:||..:|.::::|:
Mosquito   199 FLAEAKQRRAFLEAKQGLEVKMLIEEQSAEQERLLLSVLPEHVAVKMRQDL-------------- 249

  Fly   294 SQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTHLTTTLDVKKLVEALHDLFVR 358
                  .|.:|:..|:        :::..||:|::||||:|.:|.:::|...:.||:.|::||.|
Mosquito   250 ------GSTNSEQFKK--------IYMSRHENVSILYADIVGFTAISSTYSAQDLVKILNELFAR 300

  Fly   359 FDIASEEYNVLRIKFLGDCYYCVAGLANPNADHAKCCVDLGLRMIKDIRDVREKRHLNIDMRIGV 423
            ||..:|:|..||||.|||||||::|......|||..||.:||.|:|.|:.|::|.:..:|||:|:
Mosquito   301 FDRLAEKYQQLRIKILGDCYYCISGAPVERPDHAVLCVHMGLSMVKAIKYVQQKTNSPVDMRVGI 365

  Fly   424 HSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSLLDGEYFFEDGTEKARED 488
            |:|.||:|::|..:||||::||||::||::|::|..||||:|:|||..|:||:..|....:.||:
Mosquito   366 HTGAVLAGILGQRQWQFDVYSKDVELANKMESSGKAGRVHLSEKTLGFLNGEFEVEPAFGEKREE 430

  Fly   489 PVLQKHGIRTFLIKSLRAPM----H-----DPR------------RRMRERQVKKLSEASKANFM 532
             .|:..|::|:.|..:..|.    |     ||:            .|..:...|..:.|:..:
Mosquito   431 -ALRIAGLKTYFITKVLKPFCPSEHKNGSADPKDVVIEPDGPSEILREDDDDTKPANGANAGD-- 492

  Fly   533 HNST---------LHQYNQVRNQAKLEMCRELDKMPIGRIQLTKVFRRSTRLTQDEIEEETFRRN 588
            ..||         |....|.....|:.:.:||                .:|....||.::|
Mosquito   493 EPSTPGTDDKTDPLEDDTQASEDYKMRLRKEL----------------VSRDGHSEISKDT---- 537

  Fly   589 ISSCCLFFRIRNWEFQY--IKEPDVMLKYSIALAWVIYMGLLTIQLLSKDARYHYWYIDGTTIIL 651
              :..|.|..:..|..|  .:||...:....||. |.::.:|...|:......|:..:....:|:
Mosquito   538 --TIFLTFNDKTHETAYNEYREPHSAVPLLAALL-VQFVAILYALLVLPRTAVHFEIVIPPLVII 599

  Fly   652 LTMLLIVSWYKKLWIMYMSDADVSSPNGRLSGFL------FRMSDEMQRNVVIRVVMYF------ 704
            ..|:.|              :...|..|.|..|:      :..|..::::..|.:|:..
Mosquito   600 FVMVFI--------------SVAESLTGILPAFITLNSKRYNDSTSLRKSTAIIIVLLLGVSNVS 650

  Fly   705 -LIIFSY---CAVAIMQVVGCSSDEDYADLDPTYDERVQCFHPWILTNCMTLVIGMSFLFTRIPF 765
             ::..|:   .::.|..|...|::.:.|.:         |..|...:|...|::..:.:.|::..
Mosquito   651 DMLAASHRTPLSLNITNVSFASTEMEPASV---------CLFPSYFSNYTVLILIATSIITQLSH 706

  Fly   766 IIKSCFSALIMIGYAVLVVSEFNFIYANSPSTNVN-FNAKYS-HILLMIITFGIFHLMERQTEFI 828
            :.|.....:|...:..:.:...:..:.|.....:| |..:|: ..||:.:|..: ..:.|..:.:
Mosquito   707 LSKILLMIIITAIHCYVNIFHLDEAFRNEDFGIMNVFPLRYTLSALLVAVTIAL-SFLARHIDKV 770

  Fly   829 AKVDYNWKRQLIKKQEDALITNDTIKVLLTNILPTHVADFYLSNQLQ--NELYYEEYDNVAVMFA 891
            .:|.:.||.::|.::|.|.......:.|:.|:||.|||:.::.|:.:  ::||.:.|..|.|:||
Mosquito   771 DRVIFMWKTEVIDQKEKASDMRRRNEALVYNVLPMHVAEHFMGNRKRSHDDLYSQSYAEVGVLFA 835

  Fly   892 SIKNFD-------TDKIG---LRVLNEIICDFDDVLNKYSQSLRVEKIKVANWTYMAACGLDVSR 946
            |:.||.       .:..|   ||.|||:|.|||.:| :..|...:.|||....|||||.||:.||
Mosquito   836 SMPNFSDFYSEETVNNQGLECLRFLNEVISDFDALL-ELPQFQDIIKIKTIGSTYMAASGLNPSR 899

  Fly   947 SEQVNAPQMKFRNVSLMPNGRRSRYDGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVITS 1011
            ..:.:.|      ||:                          ..:::||
Mosquito   900 IVKPDDP------VSV--------------------------RWAHLAL---------------- 916

  Fly  1012 GPRISSTHNGSSSNEVVRVMAEFALDLMRTMRRFNTENMQTEYEGSTDYGMLRIGISHGRAMAGV 1076
                               :.||||:|.:.::..|        |.|.::.:|::|::||...|||
Mosquito   917 -------------------LVEFALELKKALQGIN--------EQSFNHFVLKMGVNHGPITAGV 954

  Fly  1077 VGISKPHYDIWGNPVNMASRMDSTGVPGQIQVTENTALKLREFNIQCNYRGMTFVKGRGNIPTYI 1141
            :|..|||||||||.||:||||:|||..|.|||||.|...|:.|......||:..|||:|.:.||.
Mosquito   955 IGARKPHYDIWGNTVNVASRMESTGKAGAIQVTEETCQILQTFGYTFEQRGLVAVKGKGQLMTYY 1019

  Fly  1142 IGIDSEYQFLPHRPAAPT 1159
            :      |....||..||
Mosquito  1020 L------QGKVPRPTGPT 1031

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:318454	50/249 (20%)
		Nucleotidyl_cyc_III	321..503	CDD:448371	84/181 (46%)
		Nucleotidyl_cyc_III	878..1142	CDD:448371	90/273 (33%)
Ac3	XP_061511365.1	None