DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXD and Gyc89Da

DIOPT Version :9

Sequence 1:	NP_620469.2	Gene:	ACXD / 38284	FlyBaseID:	FBgn0040507	Length:	1162	Species:	Drosophila melanogaster
Sequence 2:	NP_001036718.1	Gene:	Gyc89Da / 42001	FlyBaseID:	FBgn0038435	Length:	667	Species:	Drosophila melanogaster

Alignment Length:	444	Identity:	94/444 - (21%)
Similarity:	164/444 - (36%)	Gaps:	160/444 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   722 SSDEDYADLDPTYDER--VQCFHPWILTNCMTLVIGMSFLFTRIPFIIKSCFSALIMIGYAVLVV 784
            |:.||  ::||...||  .|.....:|...|              |.||...|.:.:....:..:
  Fly   351 SARED--EIDPATGERRSSQGLRSILLKGQM--------------FYIKDVDSLIFLCSPLIENL 399

  Fly   785 SEFNFI--YANSPSTNVN--------FNAKYSHILLMIITFGIFHLMERQTEFIAK---VDYNWK 836
            .|.:.|  |.|    ::|        ..|.:.|...:.|   :|...|::::.:.|   :..:||
  Fly   400 DELHGIGLYLN----DLNPHGLSRELVMAGWQHCSKLEI---MFEKEEQRSDELEKSLELADSWK 457

  Fly   837 RQLIKKQEDALITNDTIKVLLTNILPTHVADFYLSNQLQNELYYEEYDNVAVMFASIKNFDTDKI 901
            ||           .|.   ||.:::|..:|:   ..:|..|...:.::.|:|:|..:.|...:.:
  Fly   458 RQ-----------GDE---LLYSMIPRPIAE---RMRLSEEQVCQSFEEVSVIFLEVMNVYDEGL 505

  Fly   902 G--------LRVLNEIICDFD-DVLNKYSQSLRVEKIKVANWTYMAACGLDVSRSEQVNAPQMKF 957
            .        :..||::....| ::::.:     |.|::.....|||..|
  Fly   506 NSIQGAMQTVNTLNKVFSALDEEIISPF-----VYKVETVGMVYMAVSG---------------- 549

  Fly   958 RNVSLMPNGRRSRYDGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVITSGPRISSTHNGS 1022
                                                                  .|.::..|
  Fly   550 ------------------------------------------------------APDVNPLH--- 557

  Fly  1023 SSNEVVRVMAEFALDL-MRTMRRFNTENMQTEYEGSTDYGMLRIGISHGRAMAGVVGISKPHYDI 1086
                     ||.|.|| :|.|::|...:|     |..   .:|:||:.|..:|||||...|.|.:
  Fly   558 ---------AEHACDLALRVMKKFKAHDM-----GDV---AIRVGINSGPVVAGVVGQKVPRYCL 605

  Fly  1087 WGNPVNMASRMDSTGVPGQIQVTENTALKLREFNIQCNYRGMTFVKGRGNIPTY 1140
            :|:.||.||||:|:..|.:||:::.|..|:|:...:...||...|||:|::.||
  Fly   606 FGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVGYKVESRGTVQVKGKGDMETY 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831
		CYCc	254..476	CDD:214485
		Nucleotidyl_cyc_III	321..503	CDD:299850
		CYCc	856..1117	CDD:214485	55/270 (20%)
		Nucleotidyl_cyc_III	878..1142	CDD:299850	58/273 (21%)
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002
		HNOBA	218..476	CDD:285003	34/164 (21%)
		CYCc	457..643	CDD:214485	60/297 (20%)
		Guanylate_cyc	485..662	CDD:278633	58/270 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453998
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740