DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXD and CG31183

DIOPT Version :9

Sequence 1:	NP_620469.2	Gene:	ACXD / 38284	FlyBaseID:	FBgn0040507	Length:	1162	Species:	Drosophila melanogaster
Sequence 2:	NP_001287342.1	Gene:	CG31183 / 41927	FlyBaseID:	FBgn0051183	Length:	1417	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	75/314 - (23%)
Similarity:	156/314 - (49%)	Gaps:	54/314 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 ENLLLRYARDQERSLLLSILPAQI---ADRLQEDVKNRIERSKQQHQQQSQVD------LRRSAD 303
            ::::.|:.:|.|...::..|..::   |:.|:|.|:   ||::..|:::.:.:      |.:|..
  Fly   874 KSMIRRFNKDNETGNIVDNLLKRMELYANNLEELVE---ERTQDYHEEKKKCEKLLYQLLPQSVA 935

  Fly   304 SQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTHLTTTLDVKKLVEALHDLFVRFDIASEEYNV 368
            :|.:.  .||    :..|..:.||:.::|:|.:|.::......::|:.|:||:..||...|.::|
  Fly   936 AQLIS--GQP----VVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFDV 994

  Fly   369 LRIKFLGDCYYCVAGLANPNAD-HAKCCVDLGLRMIKDIRDVR-----EKRHLNIDMRIGVHSGD 427
            .:::.:||.|..|:||...|.: ||:....|.|.:::.:.:.|     |.|   :.:|||:|:|.
  Fly   995 YKVETIGDAYMVVSGLPIRNGNQHAREIARLALALLEAVHNFRIHHRPEDR---LKLRIGLHTGA 1056

  Fly   428 VLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSLLD------------------G 474
            .::||:|....::.::...|:.|:|:|:.|...::|:|:.|...||                  |
  Fly  1057 CVAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHISETTKEALDEFGTFVTTRRGFVPMKGKG 1121

  Fly   475 E---YFFEDGTEKAREDPVLQKHGIRTFLIKSLRAPMHDPRRRMRERQVKKLSE 525
            |   |:.|.  |..|.:.::..    :.|:.:.|:.:..|:|.......|:.||
  Fly  1122 EMLTYWLEG--EVPRPNSLISP----SKLMLTRRSSLKQPQRSQSHNLHKQYSE 1169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831	8/38 (21%)
		CYCc	254..476	CDD:214485	63/257 (25%)
		Nucleotidyl_cyc_III	321..503	CDD:299850	53/208 (25%)
		CYCc	856..1117	CDD:214485
		Nucleotidyl_cyc_III	878..1142	CDD:299850
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368
		ANF_receptor	108..473	CDD:279440
		PK_GC-A_B	589..883	CDD:270944	1/8 (13%)
		Pkinase_Tyr	613..877	CDD:285015	0/2 (0%)
		HNOBA	<893..938	CDD:285003	10/47 (21%)
		CYCc	917..1108	CDD:214485	51/199 (26%)
		Guanylate_cyc	944..1130	CDD:278633	49/188 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454014
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740