Protein Alignment ACXD and CG43373

DIOPT Version :9

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Alignment Length: 1184
• Identity: 330/1184 - (27%)
• Similarity: 517/1184 - (43%)
• Gaps: 300/1184 - (25%)

  Fly    67 LFIFIHVAVTVIHTLLL--LTTPEIKYVYVDMVAYMCSGLVIWVVLGVNFRSE-LVSKHGWVVYA 128
            :|:.:.:...:::..||  |:.|.:..:::.:|:|:..|..:.:.:.|::..: ..|.:|
  Fly   526 VFLIVMLICGIVYAFLLCILSKPAMNEIFLVLVSYVILGTFLAIEVAVSYAMQPSKSFNG----- 585

  Fly   129 TSWLAVCVMVLMDIGLNVYHATSHNDILNPIYDAYTLYAIYMFMPVPYLLQPFVLGSAVTFCYII 193
                :.|.:||                   ||..||:        :|..|:..::|..:.....:
  Fly   586 ----SACCIVL-------------------IYMTYTM--------LPLRLREALIGGILLSVVHL 619

  Fly   194 NYSFVITAKDDNQMHSI-----LNEAIYLSCVNLLGIFFRLMRDIALRTTFLDRRQYVEENLLLR 253
            .....:.|..|..:..|     |...:.|...||.|::....::.|.|..|::.||.:|..|..:
  Fly   620 YTCLRLNAMQDEAVEMIHWEELLCTLVALLLANLTGVYTHWPKEKAQRKAFIETRQCIEARLRTQ 684

  Fly   254 YARDQERSLLLSILPAQIADRLQEDVKNRIERSKQQHQQQSQVDLRRSADSQTLKRWRQPDHGTL 318
            ....|:..||||:||..:|..:::|:..: .|..|.|:                          :
  Fly   685 RENQQQERLLLSVLPRHVAMEMKDDIAGQ-PRDTQFHK--------------------------I 722

  Fly   319 FIEPHEDVTVLYADVVNYTHLTTTLDVKKLVEALHDLFVRFDIASEEYNVLRIKFLGDCYYCVAG 383
            :|:.||:|::|:||:..:|.|:.....::||..|::||.|||..:.|::.||||.||||||||:|
  Fly   723 YIQRHENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGDCYYCVSG 787

  Fly   384 LANPNADHAKCCVDLGLRMIKDIRDVREKRHLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVD 448
            |..|..|||.|.|::||.||..|..|||...:|::||:|:|:|.|..||:|..|||||:||.||.
  Fly   788 LPEPRPDHAHCAVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGLVKWQFDVWSNDVT 852

  Fly   449 IANRLEATGATGRVHVSQKTLSLLDGEYFFEDGTEKAREDPVLQKHGIRTFLIKSLRAPMHDPRR 513
            :||.:|:.|..||||::::||..|||:|..|.|....| :..|:.|.|.|:||  :...::.|.:
  Fly   853 LANHMESGGIPGRVHITKETLKCLDGDYEVEVGKGNER-NSYLKDHQIETYLI--VPGDIYRPHK 914

  Fly   514 RMRERQVKKLSEASKANFMHNSTLHQYNQVRNQAKLEMCRELDKMPIGRIQL-TKVF-----RRS 572
            :.|.|.                          |....:.:||..|..|..|. |..|     ..|
  Fly   915 KSRNRL--------------------------QVNGNISKELRMMGHGTAQKHTSKFGFGDSSES 953

  Fly   573 TRLTQDEIEEETFR----RNI--------SSCCLFFRIRNWEFQYIKEPD------------VML 613
            .:..:||:.|...|    |:|        .|..|.|:....|.:|..|||            |:|
  Fly   954 AKDPEDEVNEYLMRAIDARSIDHLRAEHCQSLLLCFKDNVLERKYASEPDRMLCVYFYCSLLVLL 1018

  Fly   614 KYSIALAWVIYMGLLTIQLLSKDARYHYWYIDGTTIILLTMLLIVSWYKKLWIMYMSDADVS--- 675
            ..||....|....|||:.|.:           |..::|..::.:|:.:|   |.:...:|:.
  Fly  1019 GTSIMRLVVFQSSLLTLALST-----------GALLLLGFLVFLVACHK---INFQLPSDIKRFS 1069

  Fly   676 ---SPNGRLSGFLFRMSDEMQRNVVIRVVMYFLIIF--SYCAVAIMQ-------VVGCSSDEDYA 728
               ..|.|:|. ||..:     :|.:.|:...|.:|  |...:.::|       |.|..|..|..
  Fly  1070 LRIHSNRRISQ-LFAFA-----SVALIVLTTLLAMFQESGRQMELLQRRRFWLDVNGSISLNDTE 1128

  Fly   729 DLDPTYD-ERVQC-----FHPWILTNCMTLVIGMSFLFTRIPFIIKSCFSALIMIGYAVLVVSEF 787
            .....|| |...|     ::.::|   :||:..||....::..|:......|:..|..:...|.
  Fly  1129 LNTKMYDAEEPDCDFYLAYNTFLL---LTLLSMMSCATYQVLRILLKLLLLLLASGSYMACSSN- 1189

  Fly   788 NFIYANSPSTN---VNFNAKYSHILLMIITFG-----IFHLMERQTEFIAKVDYNWKRQLIKKQE 844
              :|:.|...:   .|..|...:|:..|..|.     |||  ..|||...::|:.||.|..:::|
  Fly  1190 --LYSRSREMSQELANEEALLRYIIDSIFLFAFMLALIFH--SHQTEATYRLDFIWKLQATEEKE 1250

  Fly   845 DALITNDTIKVLLTNILPTHVADFYLSNQLQ-NELYYEEYDNVAVMFASIKNFDTDKIG------ 902
            |........:.||.||||.|||:.:||.:.. ::||:|:.|:|.::||||.||....:.
  Fly  1251 DMEHLQAYNRKLLENILPVHVAEHFLSREKHLDDLYHEQCDSVCILFASIPNFSEFYVELEGNNE 1315

  Fly   903 ----LRVLNEIICDFDDVLNKYSQSLR-VEKIKVANWTYMAACGLDVSRSEQVNAPQMKFRNVSL 962
                ||:|||||.|||::|::  :..| :||||....|||||.||..:..::||     |.:|:
  Fly  1316 GVECLRLLNEIIADFDELLSE--ERFRCIEKIKSTGATYMAASGLTANTCDRVN-----FSHVT- 1372

  Fly   963 MPNGRRSRYDGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVITSGPRISSTHNGSSSNEV 1027
                                                                             
  Fly  1373 ----------------------------------------------------------------- 1372

  Fly  1028 VRVMAEFALDLMR-----TMRRFNTENMQTEYEGSTDYGMLRIGISHGRAMAGVVGISKPHYDIW 1087
              .||::||.|..     .|..||...|             ||||:.|..:|||:|..||.||||
  Fly  1373 --AMADYALQLFDKIEEVNMHSFNNFRM-------------RIGINIGPVVAGVIGACKPQYDIW 1422

  Fly  1088 GNPVNMASRMDSTGVPGQIQVTE--NTALKLREFNIQCNYRGMTFVKGRGNIPTYII----GIDS 1146
            ||.||:||||||||:...||||:  ...|:.|.|.:.|  ||...|||:|::.||.:    .||:
  Fly  1423 GNAVNVASRMDSTGLVDHIQVTQEMQQILEGRGFELTC--RGSVDVKGKGSMITYFLKGRRPIDA 1485

  Fly  1147 EYQFLPHRPAAPTK 1160
            :...|......|.|
  Fly  1486 KELELAKTEVEPPK 1499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831	45/224 (20%)
		CYCc	254..476	CDD:214485	90/221 (41%)
		Nucleotidyl_cyc_III	321..503	CDD:299850	87/181 (48%)
		CYCc	856..1117	CDD:214485	90/279 (32%)
		Nucleotidyl_cyc_III	878..1142	CDD:299850	90/281 (32%)
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831	47/230 (20%)
		CYCc	686..881	CDD:214485	90/221 (41%)
		Guanylate_cyc	722..895	CDD:278633	82/173 (47%)
		DUF1053	<949..1005	CDD:283888	15/55 (27%)
		CYCc	1259..1455	CDD:214485	90/283 (32%)
		Guanylate_cyc	1285..1479	CDD:278633	90/283 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453944
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D57794at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850