DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXD and Phlpp

DIOPT Version :9

Sequence 1:	NP_620469.2	Gene:	ACXD / 38284	FlyBaseID:	FBgn0040507	Length:	1162	Species:	Drosophila melanogaster
Sequence 2:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster

Alignment Length:	153	Identity:	32/153 - (20%)
Similarity:	65/153 - (42%)	Gaps:	21/153 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   787 FNFIYANSPSTNVNFNAKYSHILLMIITFGI-FHLMERQTEF-IAKVDYNWKRQLIKKQE----D 845
            |:.....:||......:| .::|.|..|.|: .:|:.|.::. :.|.|...|.|:....:    :
  Fly   529 FHLTRTRAPSKVRPLKSK-RYVLRMASTGGLDAYLIRRTSQLRLTKPDVIQKDQIHSMPDPHVLE 592

  Fly   846 ALITNDTIKVLLTNILPTHVADFYLSNQLQNELYYEEYD--------NVAVMFASIKNFDTDKIG 902
            .:::||...:::.|.....|.|.   ::...|:..||..        ::|..||:.::.....:.
  Fly   593 LILSNDDEYLVVGNAQLWSVMDI---DRAAREIRKEENSLLAAKRLVDIAQSFAAAESLSVIVVR 654

  Fly   903 LRVLNEIICDFDDVLNKYSQSLR 925
            .|.|.   .|.|.::.:..||:|
  Fly   655 FRHLG---TDVDHLIRELKQSVR 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831
		CYCc	254..476	CDD:214485
		Nucleotidyl_cyc_III	321..503	CDD:299850
		CYCc	856..1117	CDD:214485	16/78 (21%)
		Nucleotidyl_cyc_III	878..1142	CDD:299850	12/56 (21%)
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380
		LRR_8	109..169	CDD:290566
		leucine-rich repeat	111..135	CDD:275380
		leucine-rich repeat	136..158	CDD:275380
		leucine-rich repeat	159..183	CDD:275380
		leucine-rich repeat	184..209	CDD:275380
		LRR_8	205..266	CDD:290566
		leucine-rich repeat	210..230	CDD:275380
		leucine-rich repeat	232..255	CDD:275380
		LRR_RI	<256..410	CDD:238064
		leucine-rich repeat	256..276	CDD:275380
		LRR_8	279..359	CDD:290566
		leucine-rich repeat	280..303	CDD:275380
		leucine-rich repeat	304..348	CDD:275380
		leucine-rich repeat	349..372	CDD:275380
		PP2Cc	461..655	CDD:294085	25/129 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900