DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXD and Npr3

DIOPT Version :9

Sequence 1:	NP_620469.2	Gene:	ACXD / 38284	FlyBaseID:	FBgn0040507	Length:	1162	Species:	Drosophila melanogaster
Sequence 2:	NP_032754.2	Gene:	Npr3 / 18162	MGIID:	97373	Length:	536	Species:	Mus musculus

Alignment Length:	337	Identity:	62/337 - (18%)
Similarity:	102/337 - (30%)	Gaps:	122/337 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   802 NAKYSHIL-----------LMIITFGIFHLMERQTEFIAKVDYNWKRQLIKKQEDALITNDTIKV 855
            :.:|||:.           :|:..|...|               |.|..:...:|.|..|
Mouse   163 DTEYSHLTRVAPAYAKMGEMMLALFRHHH---------------WSRAALVYSDDKLERN----- 207

  Fly   856 LLTNILPTHVADFYLSNQLQNELYYEEYDNVAVMFASIKNFDTDKIGLRVLNEIICDFDDVLNKY 920
                        .|.:.:..:|::.||     .:..|..|||..|         ..|.||::...
Mouse   208 ------------CYFTLEGVHEVFQEE-----GLHTSAYNFDETK---------DLDLDDIVRYI 246

  Fly   921 SQSLRVEKIKVANWTYMAACGLDVSR------SEQVNAPQMKFRNVSLMPNGRRSRYDGARSSNA 979
            ..|.||        ..|.|.|..:.|      ...:.:....|.|:.|.           .||:
Mouse   247 QGSERV--------VIMCASGDTIRRIMLAVHRHGMTSGDYAFFNIELF-----------NSSS- 291

  Fly   980 DGVQRVPYGNGSNIALDLDLERGQYEGNVITSGPRISSTHNGSSSNEVVRVM-------AEFALD 1037
                   ||:||       ..||....         |......||.:.|.::       .:|:::
Mouse   292 -------YGDGS-------WRRGDKHD---------SEAKQAYSSLQTVTLLRTVKPEFEKFSME 333

  Fly  1038 LMRTMRR--FNTENMQTEY-EGSTDYGMLRIGISHGRAMAGVVGISKPHYDIWGNPVNMASRMDS 1099
            :..::.:  .|.|:....: ||..|..:|.:...|....|   |.||..   .|..:........
Mouse   334 VKSSVEKQGLNEEDYVNMFVEGFHDAILLYVLALHEVLRA---GYSKKD---GGKIIQQTWNRTF 392

  Fly  1100 TGVPGQIQVTEN 1111
            .|:.||:.:..|
Mouse   393 EGIAGQVSIDAN 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831
		CYCc	254..476	CDD:214485
		Nucleotidyl_cyc_III	321..503	CDD:299850
		CYCc	856..1117	CDD:214485	51/272 (19%)
		Nucleotidyl_cyc_III	878..1142	CDD:299850	49/250 (20%)
Npr3	NP_032754.2	PBP1_NPR_C_like	49..440	CDD:107381	62/337 (18%)
		ANF_receptor	66..419	CDD:279440	62/337 (18%)
		TM_EphA1	471..502	CDD:214014
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900