Protein Alignment ACXD and gcy-33

DIOPT Version :9

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_001256392.1
• Gene: gcy-33 / 179644
• WormBaseID: WBGene00001553
• Length: 947
• Species: Caenorhabditis elegans
• Alignment Length: 718
• Identity: 132/718 - (18%)
• Similarity: 255/718 - (35%)
• Gaps: 218/718 - (30%)

  Fly   519 QVKKLSEASKANFMHNSTLHQYNQVRNQAKLEMCRELDKMP-------IGRIQLTKVFRRS---- 572
            ||:||:..|:.:.   ||..||::.......:...|:...|       .||..:..:.|..
 Worm    24 QVQKLTSLSEKSV---STHDQYSEHVVPQMFKAIHEITGTPYEQIGVLAGRFFVQFLIRNGYGDL 85

  Fly   573 ----TRLTQDEIEEETFRRNISSCCLFFRIRNWEFQYIK------------EPDVMLKYS----- 616
                .|...|      |.:.:.:...:||     |.|.|            |..::|.|.
 Worm    86 MNVMGRRFSD------FIKGLDNIHEYFR-----FSYPKLRAPSFYCKSESEDGLILHYRSRRTG 139

  Fly   617 ---------IALAWVIYMGLLTIQLLSKDARYHYWYI------DG-------------------- 646
                     :.||.|.|...:.||:|.|..:..:.::      |.
 Worm   140 YLSYVIGQLVELARVFYQLDIGIQVLKKKEKGRFTFVVLKISFDNVGLGQDLKLKERVKNLNEYL 204

  Fly   647 ---TTIILLTMLLIVSWYKKLWIMYMSDADVS-SPNGRLSGFLFRMSDEMQRNVVIRVVMYFLII 707
               |...|......:::.|||.|:......:: .||  :.|.|.....::|| ..|:.....:::
 Worm   205 PVDTKSFLQMFPFHIAFNKKLEILMAGQGLLNLMPN--IQGLLMTDVFDLQR-PCIKFTAEGIMV 266

  Fly   708 FSYCAVAIMQ---VVGCSSDEDYADLDPTYDERVQCFHPWILTNCMTLVIGMSFLFTRIPF-IIK 768
            ...|...|..   ||..:.:.....::...:::|......::.|...|. .:.::..|.|. ::|
 Worm   267 HQNCVFQIESLHPVVKQTEENITVQINDITEDKVSLEKKTVMDNEYGLE-SLPYVTLRGPITVLK 330

  Fly   769 SCFSALIMIGYAVLVVSEFNFIYANSPSTNVNFNAKYSHILLMIITFGIFHLMERQTEFIAKVDY 833
            |..:.|::   |..||...:.::......| :|.....:..:::.|.       ::::.:..:..
 Worm   331 SSETFLLL---ATCVVDTLDTMFKMGLYLN-DFGESDCNREIIMATI-------QKSDTLKTMLE 384

  Fly   834 NWKRQ---LIKKQEDALITNDTIKVLLTNILPTHVADFYLSNQLQNELYYEEYDNVAVMFASIKN 895
            |.||:   |.:...:......|.:.|||.::|..||...:.:...:  :.|.::.|::.|  |:.
 Worm   385 NEKRRSEVLTEMTREISEAKKTARTLLTQMMPYEVAQTMMRSGSVD--HCEAFECVSIGF--IRV 445

  Fly   896 FDTDKIGL--------RVLNEIICDFDDVLNKYSQSLRVEKIKVANWTYMAACGLDVSRSEQVNA 952
            .|..||.|        .:||.|....|.:::.:.    |.|::....:||.:.|
 Worm   446 CDFSKISLFIEAFEVVNLLNTIYSHLDSIVDTHG----VYKVETIGESYMISAG----------- 495

  Fly   953 PQMKFRNVSLMPNGRRSRYDGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVITSGPRISS 1017
                                            .||             |..|:..::
 Worm   496 --------------------------------CPY-------------RDDYDAEMV-------- 507

  Fly  1018 THNGSSSNEVVRVMAEFALDLMRTMRRFNTENMQTEYEG--STDYGMLRIGISHGRAMAGVVGIS 1080
                          ::..|:::..::.|       ||:.  :....:::.||..|..:.||||:.
 Worm   508 --------------SDCCLEMVSHIKSF-------EYQSHDAVKKVLIKCGIFTGPVVGGVVGVR 551

  Fly  1081 KPHYDIWGNPVNMASRMDSTG-VPGQIQVTENTALKLRE-----FNIQCNYRGMTFVKGRGNIPT 1139
            .|.|.::|:.||.||||:|:. .|..||:.:.|..::.:     |.|:  .:|..||||:|::..
 Worm   552 TPRYCLFGDTVNTASRMESSNQTPMTIQIGQRTKDRVEKQASGAFRIK--PKGNVFVKGKGDMRV 614

  Fly  1140 YII 1142
            |.|
 Worm   615 YEI 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831
		CYCc	254..476	CDD:214485
		Nucleotidyl_cyc_III	321..503	CDD:299850
		CYCc	856..1117	CDD:214485	52/271 (19%)
		Nucleotidyl_cyc_III	878..1142	CDD:299850	55/279 (20%)
gcy-33	NP_001256392.1	HNOB	2..164	CDD:377902	30/153 (20%)
		HNOBA	204..423	CDD:369471	42/233 (18%)
		CYCc	402..598	CDD:214485	54/288 (19%)
		COG5134	<595..744	CDD:227463	10/25 (40%)
		TDA11	<710..>898	CDD:293689

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910