Protein Alignment ACXD and acy-3

DIOPT Version :9

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_497765.4
• Gene: acy-3 / 175489
• WormBaseID: WBGene00000070
• Length: 1243
• Species: Caenorhabditis elegans
• Alignment Length: 1126
• Identity: 222/1126 - (19%)
• Similarity: 407/1126 - (36%)
• Gaps: 296/1126 - (26%)

  Fly    93 YVDMVAYMCSGLVIWVVLGVNFRSELVSKHGWV--VYATSWLAVCVMVLMDIGLNVYHATSHNDI 155
            |:|. .:..|..:|.:||.:...|..:...|.:  .||. |.|| :::|..:.: ::|      |
 Worm    12 YLDW-RHAASARLIRIVLFITSGSAFLRTLGHIPGFYAL-WTAV-ILLLSTVTI-IFH------I 66

  Fly   156 LNPI-----------------------YDA-----YTLYAIYMFMPVPY--LLQPFVLGSAVTFC 190
            |.|.                       |::     ..::::|.|..:|:  :|....|.|.|..|
 Worm    67 LRPARIAAFQILAGIVLLLDVAFALPGYESLFPALLAVFSLYTFFSLPFYAILATSTLISIVQTC 131

  Fly   191 YIINYSFVITAKDDNQMHSILNEAIYLSCV----NLLGIFFRLMRDIALRTTFLDRRQYVEENLL 251
                 ||::..:   .:|:  ||.:.:..|    |..||:.....|...|..||..|...|....
 Worm   132 -----SFLLFVE---PLHT--NELLAIIVVHIWTNFTGIYLCSTADRLARNAFLSARNSSEAEST 186

  Fly   252 LRYARDQERSLLLSILPAQIADRLQEDVKNRIERSKQQHQQQSQVDLRRSADSQTLKRWRQPDHG 316
            ..:..::...||.|.||..:.                 :|.:.|:.|.:             .|
 Worm   187 AEFQSNRLNKLLSSFLPYHLI-----------------NQARHQITLYK-------------PH- 220

  Fly   317 TLFIEPHEDVTVLYADVVNYTHLTTTLDVKKLVEALHDLFVRFDIASEEYNVLRIKFLGDCYYC- 380
             |:.|.:..|:|.|..:|.:..:............|.:|..|.:..:......|:...|....|
 Worm   221 -LYNETYSQVSVAYGRLVGFESVLAQCSSIDAARVLKELDSRIERLAASNGCTRVASEGITAVCS 284

  Fly   381 VAGLANPNADHAKCCVDLGLRMIKDIRDVREKRHLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSK 445
            :.|:   ::.||.......:.:...|...|:....::.:.||:.||.|.:||:|.:||.:|:...
 Worm   285 IPGI---DSQHATKLCRFSMELETLINSFRDATGADVSVCIGIDSGPVTAGVVGVSKWHYDVIGS 346

  Fly   446 DVDIANRLEATGATGRVHVSQKTLSLLDGEYFFEDGTEKAREDPVLQKHGIRTFLIKSLRAPMHD 510
            ..|.|..:::......|:||.:|...|.....||           |:|..|...|...|.:|
 Worm   347 VFDNALLMQSNATEPGVYVSNETRRFLGSTGEFE-----------LEKCPIGWKLYGHLPSP--- 397

  Fly   511 PRRRMRERQVKKLSEASKANFMHNSTLHQYNQVRNQAKLEMCRELDKMPIGRIQLTKVFRRSTRL 575
                       :|...:| .|...:.....|:|. |:.:.|...|..|...:.:..:..:....:
 Worm   398 -----------ELFPVNK-RFSLVTVPQAVNRVL-QSIVAMNPTLKTMGTNKKRKGEKSQEKFDM 449

  Fly   576 TQDEIEEETFRRNISSCCLFFRIRNWEFQYIKEPDVMLKYSIALA------WVIYMGLLTIQLLS 634
            .:.::|..|.   ||:....||....|.:|.||.|.....|:|::      :.||..|:..:|::
 Worm   450 QKKKVEHSTI---ISTLSQRFRNPGLEAEYHKETDHWFIPSLAISIFFLVVYGIYHMLVMPRLIT 511

  Fly   635 KDARYHYWYIDGTTIILLTMLLIVSWYKKLWIMYMSDADVSSPNGRLSGFLFRMSDEMQRNVVIR 699
            ..|     .|.|...::..:||:      |:|.|..         ..|.|:.|.|.....::::.
 Worm   512 SLA-----LIVGALTVMFFILLM------LYIDYFH---------TFSQFITRTSAGHAVSIILI 556

  Fly   700 VVMYFLIIFSYCAVAIMQVVGCSSDEDYADLDPTYDERVQCFHPWILTNCMTLVIGMSFLFTRIP 764
            :|:.|:     |  .|:....| ...:..|:..........|..|.:|..         :|.|.|
 Worm   557 IVILFV-----C--GIVNTFSC-PQPNAPDVCQKAHFSTYSFAMWTITTA---------VFVRFP 604

  Fly   765 FIIKSCFSALIMIGYAVLVVSEFNF---IYANSPSTNVNFNAK-------YSHILLMIITFGIFH 819
                |.:.|::      |::|...:   ||...|.   .|..:       .|..|:.:::....|
 Worm   605 ----SVYLAIL------LIISLLTYGLQIYVTRPD---EFGPREFMTELDLSCFLISLVSMVFLH 656

  Fly   820 LMERQTEFIAKVDYNWKRQLIKKQEDALITNDTIKV---LLTNILPTHVADFYLSNQLQNELYYE 881
              .|:.|.:.::|:   ..::|..|:..:.:..|.:   :|.|::|.|||...:  |...::::.
 Worm   657 --SRRCERLLRLDF---LAVVKGIEETSMKDKLINLNNQMLLNLVPAHVAPGVI--QKAGDVWHH 714

  Fly   882 EYDNVAVMFASIKNFDTD-KIGLRVLNEIICDFDDVLNKYSQSLRVEKIKVANWTYMAACGLDVS 945
            .:.:|.:.:.::..||.: :.|:..||.:...||..:..|.   .|||:|.||..|:.|.|
 Worm   715 SHQSVGIAYIAVSGFDLEGEAGINGLNYVFSHFDQAIANYK---GVEKVKSANRFYIVAVG---- 772

  Fly   946 RSEQVNAPQMKFRNVSLMPNGRRSRYDGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVIT 1010
                            |:|:.            |..|...|:..|
 Worm   773 ----------------LLPDA------------AQNVNETPWTIG-------------------- 789

  Fly  1011 SGPRISSTHNGSSSNEVVRVMAEFALDLMRTMRRFNTENMQTEYEGSTDYGMLRIGISHGRAMAG 1075
                           |::..:|.|.:    ::.:|..||   |:.       ::||:..|..:|.
 Worm   790 ---------------ELMSTLAHFII----SISQFAMEN---EFH-------VQIGVDCGSTLAF 825

  Fly  1076 VVGISKPHYDIWGNPVNMASRMDSTGVPGQIQVTENTALKLREFNIQCNYRGMTF----VKGRGN 1136
            |....:|.|:|:|..::.:..:..........|:|...|.||.       |.:.|    ||...|
 Worm   826 VANTDQPRYEIFGETLDRSRTLMQAAGHDTTLVSEEVFLALRP-------RPLRFSSQPVKVAMN 883

  Fly  1137 IPTY--IIGIDSEYQFLPHRP 1155
            :..|  :.|:......:|..|
 Worm   884 LNAYELVTGLRDVSVDIPTMP 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831	47/226 (21%)
		CYCc	254..476	CDD:214485	44/222 (20%)
		Nucleotidyl_cyc_III	321..503	CDD:299850	40/182 (22%)
		CYCc	856..1117	CDD:214485	50/261 (19%)
		Nucleotidyl_cyc_III	878..1142	CDD:299850	51/270 (19%)
acy-3	NP_497765.4	TctB	26..137	CDD:284693	25/124 (20%)
		CYCc	195..378	CDD:214485	44/217 (20%)
		Nucleotidyl_cyc_III	221..382	CDD:299850	37/174 (21%)
		CYCc	696..873	CDD:214485	51/269 (19%)
		Nucleotidyl_cyc_III	711..880	CDD:299850	48/259 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810