DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXD and gc2

DIOPT Version :9

Sequence 1:	NP_620469.2	Gene:	ACXD / 38284	FlyBaseID:	FBgn0040507	Length:	1162	Species:	Drosophila melanogaster
Sequence 2:	XP_021333059.1	Gene:	gc2 / 140425	ZFINID:	ZDB-GENE-011128-8	Length:	1120	Species:	Danio rerio

Alignment Length:	350	Identity:	74/350 - (21%)
Similarity:	150/350 - (42%)	Gaps:	78/350 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 NLLGIFFRLMRDIALRTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIADRLQEDVKNRIER 285
            |::....|::...:.....|.|.:..|    |...:.:...||..:||..:|:.|:
Zfish   819 NIIDSMLRMLEQYSSNLEELIRERTEE----LEIEKQKTEKLLTQMLPPSVAEALK--------- 870

  Fly   286 SKQQHQQQSQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTHLTTTLDVKKLVE 350
                                 |....:|:|       .|.|::.::|:|.:|.::...:..::|:
Zfish   871 ---------------------LGTTVEPEH-------FESVSLYFSDIVGFTTISANSEPIEVVD 907

  Fly   351 ALHDLFVRFDIASEEYNVLRIKFLGDCYYCVAGLANPNAD-HAKCCVDLGLRMIKDIRDVREKRH 414
            .|:||:..||.....::|.:::.:||.|...:|:..||.: ||....::.|.::..:...| .||
Zfish   908 LLNDLYTTFDAVIGNHDVYKVETIGDAYMVASGVPVPNGNRHAAEIANMALDILSAVGTFR-MRH 971

  Fly   415 L---NIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSLL---- 472
            :   .:.:|||:|:|..::||:|....::.::...|..|:|:|:||...|:||...|:.:|
Zfish   972 MPDVPVRIRIGLHTGPCVAGVVGLTMPRYCLFGDTVTTASRMESTGLPYRIHVHSSTVKILMELK 1036

  Fly   473 ------------------DGEYFF--EDGTEKAREDPVLQKHGIRTFLIKSLRAPMHDPRRRMRE 517
                              :..|:.  .||..|....|.:.|.|:.:   |..:..:....|::..
Zfish  1037 LGYRVELRARTELKGKRIEETYWLTGRDGFTKPLPVPPVLKSGLES---KDFKVMLKKAVRKIST 1098

  Fly   518 -RQVKKLSEASKANFMHNSTLHQYN 541
             |||.:|:.:.:.|.|    :|.::
Zfish  1099 VRQVAQLTLSDEGNVM----IHHHD 1119

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831	12/62 (19%)
		CYCc	254..476	CDD:214485	52/247 (21%)
		Nucleotidyl_cyc_III	321..503	CDD:299850	50/209 (24%)
		CYCc	856..1117	CDD:214485
		Nucleotidyl_cyc_III	878..1142	CDD:299850
gc2	XP_021333059.1	PBP1_sensory_GC_DEF_like	59..440	CDD:107366
		PK_GC-2D	551..815	CDD:270945
		HNOBA	<824..869	CDD:311573	10/48 (21%)
		CYCc	848..1040	CDD:214485	52/229 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810