Protein Alignment ACXD and ACXD

DIOPT Version :10

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: XP_061503573.1
• Gene: ACXD / 1269596
• VectorBaseID: AGAMI1_009197
• Length: 1215
• Species: Anopheles gambiae
• Alignment Length: 1196
• Identity: 506/1196 - (42%)
• Similarity: 738/1196 - (61%)
• Gaps: 120/1196 - (10%)

  Fly    33 KNWEWSYLVRKCRNLELEDSYDLYMRRLRVGYLSLFIFIHVAVTVIHTLLLLT-TPE-IKYVYVD 95
            |.||..:|.|:|.||.||..|..||.|::..|||:|:.:...|::.|.::::| .|. ...::.|
Mosquito    41 KKWELGFLRRECVNLGLETFYLKYMERVQRSYLSIFVVLQTFVSISHVIVIVTGKPHPTAAIHPD 105

  Fly    96 MVAYMCSGLVIWVVLGVNFRSELVSKHGWVVYATSWLAVCVMVLMDIGLNVYHA--TSHNDILNP 158
            ::.|:...|::|:.|...|:..||..:.||.|.:|.:||..|::.|:.:.:|||  |..|..|.|
Mosquito   106 LICYLFGILIVWISLFAAFKEGLVKAYPWVPYVSSSIAVITMIITDLTIPLYHAVVTFINPPLRP 170

  Fly   159 IYDAYTLYAIYMFMPVPYLLQPFVLGSAVTFCYIINYSFVITAKDDNQMHSILNEAIYLSCVNLL 223
            .|.::|:.|||:|:|:...:...:||||.:.||:|..:.:....::|....::.|.||..|:||.
Mosquito   171 SYASHTILAIYIFLPLTENIHGIILGSATSLCYLIVMTLITYRLEENTALKVITELIYFICLNLF 235

  Fly   224 GIFFRLMRDIALRTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIADRLQEDVKNRIERSK- 287
            |::|||:.::|:|.||||||:.||.||||::||:||:.|||||||...|:.:::|::..||:.:
Mosquito   236 GLYFRLINEVAIRRTFLDRRELVEGNLLLKFARNQEKELLLSILPEHTAELMEKDIRAMIEKMRN 300

  Fly   288 QQHQQQSQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTHLTTTLDVKKLVEAL 352
            .||.....::.:....:.|  :||..:  .|:::.|.:||:||||||||||:||.|.|:.||:.|
Mosquito   301 DQHNANQTINTQNFFRTGT--QWRSIN--KLYVQKHTNVTILYADVVNYTHMTTQLPVRTLVDVL 361

  Fly   353 HDLFVRFDIASEEYNVLRIKFLGDCYYCVAGLANPNADHAKCCVDLGLRMIKDIRDVREKRHLNI 417
            |:|||:||.||:|:|||||||||||||||:|:...|..|||.||:|||||||||||||..|.|||
Mosquito   362 HELFVKFDEASKEFNVLRIKFLGDCYYCVSGVPVRNKYHAKSCVNLGLRMIKDIRDVRMSRDLNI 426

  Fly   418 DMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSLLDGEYFFEDGT 482
            |||||:|||.::||||||.|||:|||||||.|||::|:||..|:|||:.:||.||||||.||:||
Mosquito   427 DMRIGIHSGSIISGVIGACKWQYDIWSKDVIIANKMESTGEAGKVHVTMQTLELLDGEYIFEEGT 491

  Fly   483 EKAREDPVLQKHGIRTFLIKSLRAPMHD-----------PRRRM----RERQVKKLSEASKANFM 532
            .:|::||:|.||.|:||||  :..|.:|           |..||    :.:.:||.......|||
Mosquito   492 PQAKDDPILVKHNIQTFLI--VPQPGYDDGSFFTVQEPGPSSRMSSGVKRKTIKKERSLVTRNFM 554

  Fly   533 HNSTLHQYNQVRNQAKLEMCRELDKMPIGRIQLTKVFRRSTRLTQDE----------------IE 581
            .|| :.|:.::.....:||..||::|||||.|..|:|.......|:.                .|
Mosquito   555 QNS-MEQFREIMKLTNVEMAYELERMPIGRFQFNKLFSSYKTYMQEPSHTSAPARTVENGPRCSE 618

  Fly   582 EETFR-RNISSCCLFFRIRNWEFQYIKEPDVMLKYSIALAWVIYMGLLTIQLLSKDARYHYWYID 645
            |:|.| .|:|...:.|..:.||..|::|||:|||||:.:::::::.:|.||:|:..:..::|.::
Mosquito   619 EDTNRLDNMSPFFMCFENKRWELSYLQEPDLMLKYSVLMSFIVFVCILLIQILNDASGIYFWLLN 683

  Fly   646 GTTIILLTMLLIVSWYKKLWIMY----MSD-ADVSSPNGRLSGFLFRMSDEMQRNVVIRVVMYFL 705
            |.:..||...:.::|:||:|.:|    :.| ..|..|..|:....:..|:::..|.|||.|:|.:
Mosquito   684 GLSGALLLAFIPITWFKKVWDVYTPYSIDDLLRVRKPQSRVMRIFYDFSNDIMSNFVIRTVIYLI 748

  Fly   706 IIFSYCAVAIMQVVGCSSD---------------------EDYADLDPTYDERVQCFHPWILTNC 749
            .|......::|.::.|:.|                     |:....||.  .:..|.:||.:|.|
Mosquito   749 TIALLVVCSLMYLIECNYDLLEQTSTTSVPVSDNLTSLFQENQTSPDPM--AKNFCTNPWSVTQC 811

  Fly   750 MTLVIGMSFLFTRIPFIIKSCFSALIMIGYAVLVVSEFNFIYANSPSTNVNFNAKYSHILLMIIT 814
            :||.|||:|||.||.|::|:....||...|...:..:..:.:.:|.|.|...:.|.||::|::..
Mosquito   812 LTLAIGMAFLFLRIHFLLKAAVGLLIFFFYCWAIFDDLYYYFDSSASMNPGLDPKVSHLMLILFI 876

  Fly   815 FGIFHLMERQTEFIAKVDYNWKRQLIKKQEDALITNDTIKVLLTNILPTHVADFYLSNQLQNELY 879
            ..|||.::||:|:||:.|||||:||:|::|:|.:|..|.|:|:.||||||||:.|::.||:||.|
Mosquito   877 VIIFHWIDRQSEYIARTDYNWKQQLLKQKEEAEVTKQTNKILVENILPTHVAEIYINRQLKNEFY 941

  Fly   880 YEEYDNVAVMFASIKNF--------DTDKIGLRVLNEIICDFDDVLNKYSQSLRVEKIKVANWTY 936
            .|||:|||||||:|.|.        :.:|..|:||||||||||:.|..:...|:|||||||.|||
Mosquito   942 NEEYENVAVMFATITNMEVNTDISVENEKSVLKVLNEIICDFDERLQYFDGYLKVEKIKVAGWTY 1006

  Fly   937 MAACGLDVSRSEQVNAPQMKFRNV------SLMPNGRRSRYDGARSSNADGVQRVPYGNGSNIAL 995
            |||||||..|.:. ::....:|:|      |||.|||||                     .|...
Mosquito  1007 MAACGLDPGRCDS-SSSLSGYRSVSGMTRTSLMTNGRRS---------------------LNPRT 1049

  Fly   996 DLDLERGQYEGNVITSGPRISSTHNGSSSNEVVRVMAEFALDLMRTMRRFNTENMQTEYEGSTDY 1060
            .|::   .::.:..|.    |::.|...||.|..|||||||:|||.:|.|:.||.:     .|..
Mosquito  1050 SLEV---AHKASTSTR----SNSSNSRHSNNVTIVMAEFALELMRVLRDFSNENFK-----QTSP 1102

  Fly  1061 GMLRIGISHGRAMAGVVGISKPHYDIWGNPVNMASRMDSTGVPGQIQVTENTALKLREFNIQCNY 1125
            |:||:|||||:.||||||.|||.||||||.|||||||||||.||:||||:.:|..|:.:..||:|
Mosquito  1103 GLLRVGISHGKVMAGVVGSSKPLYDIWGNAVNMASRMDSTGRPGRIQVTKESAEVLQSYGYQCDY 1167

  Fly  1126 RGMTFVKGRGNIPTYIIGIDSEYQFL 1151
            ||..||||||.||||.:.|.|:.:||
Mosquito  1168 RGEIFVKGRGKIPTYFLKIGSDLKFL 1193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:318454	93/245 (38%)
		Nucleotidyl_cyc_III	321..503	CDD:448371	125/181 (69%)
		Nucleotidyl_cyc_III	878..1142	CDD:448371	135/277 (49%)
ACXD	XP_061503573.1	None