Protein Alignment ACXD and gucy2g

DIOPT Version :9

• Sequence 1: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: XP_009305067.2
• Gene: gucy2g / 100333350
• ZFINID: ZDB-GENE-130531-70
• Length: 1127
• Species: Danio rerio
• Alignment Length: 1129
• Identity: 210/1129 - (18%)
• Similarity: 362/1129 - (32%)
• Gaps: 457/1129 - (40%)

  Fly   310 WRQPDHGTLFIEPHEDVTVLYADVVNYTHLTTTLDVKKLVEALHDLFVRFDIASEEYNVLRIKFL 374
            |..|..|.:...|..|...:|.     |::.....:|::.|.|               :..::|.
Zfish   127 WNIPMFGFVGQTPKMDNIQVYD-----TYIKIVPPLKRVGEIL---------------LKALEFF 171

  Fly   375 GDCYYCVAGLANPNAD------------------HAKCCVDLGLRMIKDIRDVRE-KRHLNI--- 417
            |   :...|:....||                  .:|..|.:|::.  |..|:.: ||:|.|
Zfish   172 G---WKHVGMIGGGADANTWDSVEALWKSVDQQLRSKVTVTMGIKF--DTSDLEQAKRNLQIISK 231

  Fly   418 --------------------DMRIGVHSGDVLSGVIGAAKWQFDI-------WSKDVDIANRLEA 455
                                ..::|:.||:.:..::    .||::       |...|...||...
Zfish   232 VARVVVVLANAEDSTAMMIEAQKLGLMSGEYVFLLV----QQFEVSGKVDNLWKTSVSETNRTML 292

  Fly   456 TGATGRVHVSQKTLSLLDGEYFFEDGTEKAREDPVLQK-HGIRTFLIKSLRAPMHD--------- 510
            ........:::|:....|...||:...:|.:.||.... ..::.  :.|..|.:||
Zfish   293 KAFDMVFVLAEKSYDGYDYYDFFDQAYDKLKGDPFYSNLSSVKE--VSSYAAYLHDAVLLYAMGL 355

  Fly   511 --------PRRRMRERQVKKLSEASKANFMHNSTLHQYNQV--RN-----------QAKLEMCRE 554
                    ..|..|| .|:||.:.:...|...|.|..:::.  ||           :..::....
Zfish   356 KEAFKSGKDIRHGRE-IVQKLRDRTSIRFYGASGLVHFDEYGERNLDYSVYDLQQTETLIQFVSV 419

  Fly   555 LD-----KMPIGRIQLTKVFRRSTRLTQDEIEEETFRRNISSCCLFFRIRNWEFQYIKEPDVMLK 614
            ||     ||....::.:.:..::.:...|.          .||.....:..|....|.    :|.
Zfish   420 LDFDSHTKMIKPTLRFSNIVWQNGKPPTDN----------PSCGFDNELCEWLDNEIS----LLV 470

  Fly   615 YSIAL-----AWVIYMGLLTIQLLSKDARY---HYWYIDGTTIILL-----TMLLIVSWY----- 661
            ..:||     |.|..:.|||:|.|...:|.   ::|.|:.:.|.:|     |.:|.|:..
Zfish   471 LLVALPLIGVAAVSLITLLTLQKLRLQSRLDESNWWLINYSDITILREPKGTQILSVNTTPSKCG 535

  Fly   662 ----------------------------KKLWIMYMSD---ADVSSPNGRLSGFLFRMSDEMQR- 694
                                        .::.|.|:.:   .|:..|:....   |.|..||:.
Zfish   536 SGGSQSMLSSNSCNTREAIYATVGLFQGNEVGIKYLKNQIIPDIKKPSIIAE---FNMLKEMKHE 597

  Fly   695 -------------NVVIRVVMY--------------------FLIIFSYCAVAIMQVVGCSSDED 726
                         ||.| |:.|                    |.:.|:|..|..|:.:..||.:.
Zfish   598 NLVQFFGVCIDPPNVCI-VMQYCKKGSLKDVLGNHEIDLDWMFKLSFAYDIVNGMEYIHKSSLKS 661

  Fly   727 YADLDPT---YDERVQ------------C----------------------------FHPWILTN 748
            :.:|.|:   .|.|:|            |                            |:|:..|.
Zfish   662 HGNLRPSTCLVDSRLQIKLSGFGLWEFKCGTKHRLIPLDSPKYEEMYWTAPEFLREIFYPFNGTQ 726

  Fly   749 -----CMTLVIGMSFLFTRI-PF---------IIKS------------------CFSALIMIGYA 780
                 ...::|......|.: |:         |||.                  |...||.:..|
Zfish   727 KGDVYSFAIIIRELIYSTEVGPYHDVHLEPKEIIKQLRTPMSEEPLRPTLSADICDERLIPLIKA 791

  Fly   781 VLVVSE-------FNFI-----------YANSPSTNVNFNAKYSHILLMIITFGIFHLMERQTEF 827
            ..  ||       |..|           :||.....||...||::.|..::.       ||.::.
Zfish   792 CW--SENPDHRPPFGSIRRQLRDACPESHANILDNMVNKLEKYANHLEEVVE-------ERTSQL 847

  Fly   828 IAKVDYNWKRQLIKKQEDALITNDTIKVLLTNILPTHVADFYLSNQLQNELYYEEYDNVAVMFAS 892
            ..:          |.:.|.         ||:::||.::||..::.:   .:....|:.|.:.|:.
Zfish   848 TVE----------KSRADK---------LLSSMLPRYIADQLMAGK---SVEPRSYEMVTIFFSD 890

  Fly   893 IKNFDT--------DKIGLRVLNEIICDFDDVLNKYSQSLRVEKIKVANWTYMAACGLDVSRSEQ 949
            |..|.|        :.:.|  ||::...|||::..|.    |.|::.....||.|.||.:|
Zfish   891 IVGFTTMCSVSSALEVVTL--LNDLYSLFDDIIKLYD----VYKVETIGDAYMVASGLPIS---- 945

  Fly   950 VNAPQMKFRNVSLMPNGRRSRYDGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVITSGPR 1014
                                                                             
Zfish   946 ----------------------------------------------------------------- 945

  Fly  1015 ISSTHNGSSSNEVVRVMAEFALDLMRTMRRFNTENMQTEYEGSTDYGMLRIGISHGRAMAGVVGI 1079
                 ||:...|.:..|   ||..:.:::||...::..|...      |||||:.|..:|||||.
Zfish   946 -----NGTLHAEEISTM---ALHFLSSIKRFKIRHLPNERLA------LRIGINSGPVVAGVVGS 996

  Fly  1080 SKPHYDIWGNPVNMASRMDSTGVPGQIQVTENTA---LKLREFNIQCNYRGMTFVKGRGNIPTYI 1141
            :.|.|.::|:.||.||||:|..:|.:|.::::||   |.:..|.::  .||...:||:|...|:
Zfish   997 TMPRYCLFGDTVNTASRMESNSLPLKIHISQSTADILLTIGTFELE--ERGDIEIKGKGTQKTF- 1058

  Fly  1142 IGIDSEYQFLPHRPA---APTKED 1162
                    :|..:|.   .||.:|
Zfish  1059 --------WLLSKPGFTFPPTGQD 1074

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831
		CYCc	254..476	CDD:214485	35/214 (16%)
		Nucleotidyl_cyc_III	321..503	CDD:299850	37/231 (16%)
		CYCc	856..1117	CDD:214485	62/271 (23%)
		Nucleotidyl_cyc_III	878..1142	CDD:299850	63/274 (23%)
gucy2g	XP_009305067.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810