Protein Alignment CG9018 and RPRD2

DIOPT Version :10

• Sequence 1: NP_647701.1
• Gene: CG9018 / 38283
• FlyBaseID: FBgn0035318
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_056018.2
• Gene: RPRD2 / 23248
• HGNCID: 29039
• Length: 1461
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 84/377 - (22%)
• Similarity: 151/377 - (40%)
• Gaps: 72/377 - (19%)

  Fly     6 DSALLKKLAELNSSQQSIQTLSLWLIHHRKHSAAIVRTWQRELENVPEPKKLTFMYLANDVIQNS 70
            :|:|.:|...:.::.:|||.||.|.|.::||.:.||..|.:.|.....|.:|...|||||||||.
Human    24 ESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNC 88

  Fly    71 KKKGPEYGKE-YSLVLGKVFAHIGEKCNSDKLLGSLGRILNIWLERGVYDPKTIADWRSRLHKEA 134
            |:|.....:| ::.||.:..|.:.:...|.    |:.||..||.:|.||..:.|...|..|
Human    89 KRKNAIIFRESFADVLPEAAALVKDPSVSK----SVERIFKIWEDRNVYPEEMIVALREAL---- 145

  Fly   135 PGSSSSSNGKTNGDSEKPEKEKDHGGSGKPEKSERREKRKHEDRHSKSKRSRHHVQGSSANSAPP 199
                 |:..||       :|:.....:.:|.|..::.:                   :|.|....
Human   146 -----STTFKT-------QKQLKENLNKQPNKQWKKSQ-------------------TSTNPKAA 179

  Fly   200 TEEVVSVEPENGHTPPYLPLGEPPEPEELIRALTSIENSASSDAVVRERIAKLPQEISEISCISK 264
            .:..:..|..:               :.||..|...:.|.....:..::::.:..::.....:..
Human   180 LKSKIVAEFRS---------------QALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKC 229

  Fly   265 LEDKDKAKELAIQVNEAVDLLNDYNARLAAEMEERSKLATMLRD----FQAEQKELLSQAEQRLD 325
            |:||...|:.:.:..||...|.::...|..:::....|...|.:    ::|:.||:...|    :
Human   230 LKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVA----N 290

  Fly   326 EHKKKLAKMLGLQKEIHDHLSNLPDLTR---------LPDVTGGLAPLPSAG 368
            .:|....::..|:|::....|.|||...         .|..||..:|....|
Human   291 AYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMG 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9018	NP_647701.1	CID_RPRD1	4..132	CDD:340799	45/126 (36%)
		CREPT	229..372	CDD:465181	29/153 (19%)
RPRD2	NP_056018.2	CID_RPRD2	27..146	CDD:340798	44/131 (34%)
		PRK03918	<142..>318	CDD:235175	36/229 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	311..438		9/32 (28%)
		PHA03247	<314..587	CDD:223021	7/29 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	469..504
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..623
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	696..849
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	900..997
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1016..1102
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1132..1312
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1340..1461