Protein Alignment CG15820 and EPHX2

DIOPT Version :10

• Sequence 1: NP_647696.1
• Gene: CG15820 / 38277
• FlyBaseID: FBgn0035312
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_001970.2
• Gene: EPHX2 / 2053
• HGNCID: 3402
• Length: 555
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 68/324 - (20%)
• Similarity: 119/324 - (36%)
• Gaps: 77/324 - (23%)

  Fly    23 WYGNRADRPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSSRLPPGVPYNVYDYVF-I 86
            ||..|...|.||..|:                  .||.:|:.|:|.||     .|..:.:|.. :
Human   271 WYSWRYQIPALAQAGY------------------RVLAMDMKGYGESS-----APPEIEEYCMEV 312

  Fly    87 IPRVMKEF----GWSKVSLMGHSLGGVMSFMYAAMAPSTVDMIISLDV-LLPRRIE-DPSKLTK- 144
            :.:.|..|    |.|:...:||..||::.:..|...|..|..:.||:. .:|.... .|.:..|
Human   313 LCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKA 377

  Fly   145 ----DIEGYLLEERRQADGTEHEPPSFTLSKLRETLARNSNNSVPQHLADHMLHRQVAKSNMY-- 203
                |.:.|.     |..|.........||:..::|.|.|:.||..      :|:......::
Human   378 NPVFDYQLYF-----QEPGVAEAELEQNLSRTFKSLFRASDESVLS------MHKVCEAGGLFVN 431

  Fly   204 -PEKVFFSR---DGRVKFYHIFDIENGL--ALEMARRIEKK--------------PYLVIKGSLS 248
             ||:...||   :..::||.....::|.  .|...|.:|:.              |.|::.....
Human   432 SPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKD 496

  Fly   249 PFVGPRCNETMSILSHDNPNFEFYEVEGGKHHVHLHAAEECARYIVPFI----RNHRPPRSSKL 308
            ..:.|:.::.|....   |:.:...:|...|...:....|..:.::.::    ||  ||..||:
Human   497 FVLVPQMSQHMEDWI---PHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARN--PPVVSKM 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15820	NP_647696.1	MenH	19..300	CDD:440361	63/314 (20%)
EPHX2	NP_001970.2	Phosphatase	1..224
		HAD_sEH-N_like	3..214	CDD:319790
		Epoxide hydrolase	235..555		67/322 (21%)
		Abhydrolase_1	259..531	CDD:395444	61/296 (21%)
		Microbody targeting signal. /evidence=ECO:0000255	553..555		1/1 (100%)