DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15879 and kraken

DIOPT Version :9

Sequence 1:	NP_647694.1	Gene:	CG15879 / 38274	FlyBaseID:	FBgn0035309	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001259847.1	Gene:	kraken / 33265	FlyBaseID:	FBgn0020545	Length:	331	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	102/307 - (33%)
Similarity:	170/307 - (55%)	Gaps:	28/307 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FKEVRIPAPWGHISGRWYGNRTERPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSAH 70
            ::|..|..|||.:..:|:|::..:||:|:|||.||.|:||||.||||....:|.|||||||:|:|
  Fly    39 WEEFSIAVPWGTVEAKWWGSKERQPIIALHGWQDNCGSFDRLCPLLPADTSILAIDLPGHGKSSH 103

  Fly    71 IQPGMHYAVN-DYVLIIPRVMKEYGWSKVSLMGHSLGGIISFVYTSLAPDTVDMVISLDILLPLS 134
            ...||.|.:. |.:.:|.|::::|.|..|:|:||||||.::|:|.:..|..|:.:|::||..|..
  Fly   104 YPMGMQYFIFWDGICLIRRIVRKYNWKNVTLLGHSLGGALTFMYAASFPTEVEKLINIDIAGPTV 168

  Fly   135 KDPKTVIKYLNHSLDKHL----VEEERQVEGNLHEPPSYTLAQLTQVLAKGSDNSVTPEFAQHLL 195
            :..:.:.:....:|||.|    :.|.:|        |.|:..::.:::....|.||.....:.|:
  Fly   169 RGTQRMAEGTGRALDKFLDYETLPESKQ--------PCYSYDEMIKLVLDAYDGSVDEPSVRVLM 225

  Fly   196 HRQVSKSQLYPDR--FFFSRDGRVKYYSHLQMEPEFGEALVKRIRRIPCLI-----IKGSKSDFV 253
            :|.:..:   |.:  :.|:||.|:| .|.|.|..  .|..:...|:|.|.:     |.|.|.:..
  Fly   226 NRGMRHN---PSKNGYLFARDLRLK-VSLLGMFT--AEQTLAYARQIRCRVLNIRGIPGMKFETP 284

  Fly   254 EARTEKAVAILRQNNPHFEFYEVEGGTHHVHLHAAEECARYIVPFIR 300
            :...: .:|.||:|.....:.||. ||||:||...:..|.:|:.|::
  Fly   285 QVYAD-VIATLRENAAKVVYVEVP-GTHHLHLVTPDRVAPHIIRFLK 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15879	NP_647694.1	MhpC	29..302	CDD:223669	95/284 (33%)
CG15879	NP_647694.1	Abhydrolase	47..>109	CDD:304388	31/62 (50%)
kraken	NP_001259847.1	MhpC	61..329	CDD:223669	95/283 (34%)
kraken	NP_001259847.1	Abhydrolase_5	63..>159	CDD:289465	47/95 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439855
Domainoid	1	1.000	47	1.000	Domainoid score	I11659
eggNOG	1	0.900	-	-		E2759_KOG1454
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I2617
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D109693at6656
OrthoFinder	1	1.000	-	-		FOG0001238
OrthoInspector	1	1.000	-	-		otm42436
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43329
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4622
SonicParanoid	1	1.000	-	-		X774
	11	10.930