Protein Alignment CG15879 and EPHX4

DIOPT Version :9

• Sequence 1: NP_647694.1
• Gene: CG15879 / 38274
• FlyBaseID: FBgn0035309
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_775838.3
• Gene: EPHX4 / 253152
• HGNCID: 23758
• Length: 362
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 62/312 - (19%)
• Similarity: 112/312 - (35%)
• Gaps: 80/312 - (25%)

  Fly    24 GNRTERPILAIHG-------WLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRS---AHIQPGMHYA 78
            |.|.:..:|.:||       |...|..|.      .:| .|:.:||.|:|.:   .|.|   :|.
Human    89 GERGKPLMLLLHGFPEFWYSWRYQLREFK------SEY-RVVALDLRGYGETDAPIHRQ---NYK 143

  Fly    79 VNDYVLIIPRVMKEYGWSKVSLMGHSLGGIISFVYTSLAPDTVDMVISLDILLPLSKDPKTVIKY 143
            ::..:..|..::...|:||..|:||..||:|:::.....|:.|..:|.::.     ..|....:|
Human   144 LDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINF-----PHPNVFTEY 203

  Fly   144 -LNHSLDKHLVEEERQVEGNLHEPPSYTLAQLTQVLAKGSDNSVTPEF---------AQHLL--H 196
             |.|             ...|.:...|...|:...          |||         .:||.  |
Human   204 ILRH-------------PAQLLKSSYYYFFQIPWF----------PEFMFSINDFKVLKHLFTSH 245

  Fly   197 R--------QVSKSQLYPDRFFFSR----DGRVKYYSHL-QMEPEFGEALVKRIRRIPCLIIKGS 248
            .        |::...|....:.||:    .|.:.:|.:: ...|     |...:...|.|::.|.
Human   246 STGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLP-----LKHHMVTTPTLLLWGE 305

  Fly   249 KSDFVEARTEKAVAILRQNNPHFEFYEVEGGTHHVHLHAAEECARYIVPFIR 300
            ...|:|....:...|..:|  :|....:...:|.:.....:...:.|..|::
Human   306 NDAFMEVEMAEVTKIYVKN--YFRLTILSEASHWLQQDQPDIVNKLIWTFLK 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15879	NP_647694.1	MhpC	29..302	CDD:223669	60/307 (20%)
		Abhydrolase	47..>109	CDD:304388	18/64 (28%)
EPHX4	NP_775838.3	MhpC	76..350	CDD:223669	60/305 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142117
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840