DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15879 and serhl2

DIOPT Version :9

Sequence 1:	NP_647694.1	Gene:	CG15879 / 38274	FlyBaseID:	FBgn0035309	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001096280.2	Gene:	serhl2 / 100124846	XenbaseID:	XB-GENE-943365	Length:	304	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	100/316 - (31%)
Similarity:	156/316 - (49%)	Gaps:	43/316 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KEVRIPAPWGHISGRWYGNRTERPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSAHI 71
            ||:|...|||.::.:.:|....||:|.:||||||..||||||||||:....:.:|..|||.|:|:
Frog     6 KELRFTVPWGQLAAKAWGPSDGRPVLCLHGWLDNANTFDRLIPLLPNDHHFVALDFSGHGLSSHM 70

  Fly    72 QPGMHYAVNDYVLIIPRVMKEYGWSKVSLMGHSLGGIISFVYTSLAPDTVDMVISLDI--LLPLS 134
            ..|:.|...|||..:.||:.:.||.:.|:||||:||::..::.|:.|..|..:|.||.  ..|::
Frog    71 PEGVRYQHVDYVSDVHRVVTQLGWRQFSIMGHSMGGVVGGLFASVFPKLVKNLILLDSYGFFPVN 135

  Fly   135 KDP-----KTVIKYLNHSLDKHLVEEERQVEGNLHEPPSYTLAQLTQVLAKGSDNSVTPEFAQHL 194
            .|.     |.:|.|.:..        |....|.::.|.. .|.:|.:     ::.|:|.|.|:.|
Frog   136 ADMIQTHLKKIISYYSRL--------EGVSAGKIYSPEG-ALQRLLE-----ANVSLTQETAKLL 186

  Fly   195 LHRQVSKSQLYPDRFFFSRDGRVKYYSHLQMEPEFGEALVKRIRRIPCLII--KGSKSDFVE-AR 256
            |.|   .::.......||||.||...:.|.:..|....::.:|:....:|:  :|..:|.:. ..
Frog   187 LER---GTKTVEGGVVFSRDIRVTVNNSLPLSTEQCVLMLSKIQADVHIIMANEGLTADMMRGVY 248

  Fly   257 TEKAVAILRQNNPHFEFYE---------VEGGTHHVHLHAAEECARYIVPFIRHHR 303
            |:...|:|:      .|.|         |..|.|.|||:..|:.|..|..|: |.|
Frog   249 TDVGQALLK------GFRESLKERCQVTVVDGNHFVHLNEPEKVAGIINDFL-HAR 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15879	NP_647694.1	MhpC	29..302	CDD:223669	91/291 (31%)
CG15879	NP_647694.1	Abhydrolase	47..>109	CDD:304388	28/61 (46%)
serhl2	NP_001096280.2	MhpC	16..297	CDD:223669	93/304 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I4225
OMA	1	1.010	-	-		QHG51866
OrthoDB	1	1.010	-	-		D1285824at2759
OrthoFinder	1	1.000	-	-		FOG0001238
OrthoInspector	1	1.000	-	-		mtm9351
Panther	1	1.100	-	-	O	PTHR43329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X774
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.080