Protein Alignment CG15822 and Sestd1

DIOPT Version :10

• Sequence 1: NP_001137872.2
• Gene: CG15822 / 38273
• FlyBaseID: FBgn0035308
• Length: 1267
• Species: Drosophila melanogaster
• Sequence 2: NP_780674.1
• Gene: Sestd1 / 228071
• MGIID: 1916262
• Length: 696
• Species: Mus musculus
• Alignment Length: 733
• Identity: 185/733 - (25%)
• Similarity: 324/733 - (44%)
• Gaps: 104/733 - (14%)

  Fly     5 VLNALQTRSAYLSGGFDRQKRIVFVVNAFNDLQLWNRRYLQVTLDYLKRSLSASVLQNGVSVVVN 69
            :|..|:.:.|:||||.||:..::..:...  |:..:...|.||||||....|......|.:|:|:
Mouse     6 ILPILKKKLAFLSGGKDRRSGLILTIPLC--LEQTSMDELSVTLDYLLSIPSEKCKARGFTVIVD 68

  Fly    70 AQESSSRISRQQVRQIYALFGGDINVDLYLVRAEGFWEKHVEP-C---TKSQVKGEPLVLSKARL 130
            .::|...:.:..|..:..:...:::: :.:|:.:.||:|.|.. |   .|.::..|.:::|..:|
Mouse    69 GRKSQWNVVKTVVLMLQNVVPAEVSL-VCVVKPDEFWDKKVTHFCFWKEKDRLGFEVILVSANKL 132

  Fly   131 FKFIEPQNLPEELGGTLQFNYDLWLQQRKSIDEFTKSHVQTLASMEKLLALLR---EHKSLRPAE 192
            .::|||..|.|:.||:|.:::..||.:|...::|||.....|..    |||:.   :..:.:..|
Mouse   133 TRYIEPCQLTEDFGGSLTYDHMDWLNKRLVFEKFTKESTSLLDE----LALINNGSDKGNEQEKE 193

  Fly   193 ADVELKKCAQMHAGVQNDIETAIDLGNAILA-----RFNEVYETHSPPPQAVAPASESPAGPPPI 252
            ..|:|.....:      |.||.:..|:.:|:     |||          .:....|.||.....:
Mouse   194 RSVDLNFLPSV------DPETVLQTGHELLSELQQRRFN----------GSDGGVSWSPMDDELL 242

  Fly   253 AAHSASAGSPQKPLLPPDLACERTRIELRLNEIEKKQTAIRTAWLELLRSLREARELSTLEDGVS 317
            |       .||...|...|..:.||.:                  |:.|...:..:|..::..|.
Mouse   243 A-------QPQVMKLLDSLREQYTRYQ------------------EVCRQRSKRTQLEEIQQKVM 282

  Fly   318 FVTNWILQEAELLLSRQRSVAGDVRGCEALRSAHDQLELECRETYGCYAELLYKIEKFAAERQAS 382
            .|.||:.......|..|..:...:|..:||:..|:::|.:..|.:..|.||..:|   ||...|.
Mouse   283 QVVNWLEGPGSEQLRAQWGIGDSIRASQALQQKHEEIESQHSEWFAVYVELNQQI---AALLNAG 344

  Fly   383 SKDMDRCQDLLSQRDFMQFVCRSFAKRLERRRNVLMTALRFH----RLLDQFEDLLATGNHVVEV 443
              |.:...:|.|.:..:..||...|.:||.|:|:|..||.||    .|..|.:.||.    ::.|
Mouse   345 --DEEDLVELKSLQQQLSDVCYRQASQLEFRQNLLQAALEFHGVAQDLSQQLDGLLG----MLCV 403

  Fly   444 DSRSLDWPEAEQLLMQLNKNQEMLGHVE---RELVREGEKLSDMLAMPVKDALGRDLQLDYSAEI 505
            |....|....:|.|..|   :|.|..|:   :.|..:|:.|.|.::.....|.|:|:.::....:
Mouse   404 DVAPADGASIQQTLKLL---EEKLKSVDVGLQGLREKGQGLLDQISNQASWAYGKDVTIENKENV 465

  Fly   506 AQLRRQIDESRRRRQVCGHRLALQRLTLEQVTHIHAYEEDARRARDWLQELYAVLLRCHSHVGCN 570
            ..::..:::.:.|:|.|...:.::||.:.|:..:...||||.:|.:||.||...||:.|..:|.:
Mouse   466 DHIQGVMEDMQLRKQRCEDMVDVRRLKMLQMVQLFKCEEDASQAVEWLSELLDALLKTHIRLGDD 530

  Fly   571 IHEIQLQKDELQGFEETGRSIYHYGCQLLEASQTLRLCCKLEPSSFRSQSNSSQGFISDELQHTW 635
            ..|.::..::.:.|.:..:|.|.||.|||:|  |:.||     .|.|..|.|| |.....|...|
Mouse   531 AQETKVLLEKHRKFVDVAQSTYDYGRQLLQA--TVVLC-----QSLRCTSRSS-GDTLPRLNRVW 587

  Fly   636 HSLQSVAQEQMTRLRVSAVFHRSVEAYYR-------------QLREL----RPLLTKELSAQLQQ 683
            ......::|::.||.::..||.:.|...:             |..|:    :.||.:.....:..
Mouse   588 KQFTVASEERVHRLEMAIAFHSNAEKILQDCPEEPEAMNDEEQFEEIEAIGKSLLDRLTIPVVYP 652

  Fly   684 QQRQQHNRSSSGIGSDAE 701
            ...:|:..|.|.:.|.||
Mouse   653 DGTEQYFGSPSDMASTAE 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15822	NP_001137872.2	CRAL_TRIO_2	25..152	CDD:463965	32/130 (25%)
		SPEC	298..526	CDD:413338	60/234 (26%)
		SPEC	420..649	CDD:413338	65/235 (28%)
Sestd1	NP_780674.1	CRAL_TRIO_2	33..153	CDD:463965	32/122 (26%)
		SPEC	273..478	CDD:413338	55/216 (25%)
		Spectrin 1	275..378		29/107 (27%)
		Spectrin 2	381..494		28/119 (24%)
		SPEC	413..605	CDD:413338	56/202 (28%)
		Spectrin 3	500..602		36/109 (33%)