DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and AVT4

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_014298.1	Gene:	AVT4 / 855622	SGDID:	S000005045	Length:	713	Species:	Saccharomyces cerevisiae

Alignment Length:	456	Identity:	116/456 - (25%)
Similarity:	201/456 - (44%)	Gaps:	85/456 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 KNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKR 104
            |..|:..:.|...||:.:|||||.:|:||.:.|......:....|..:.:|.:||::.      :
Yeast   294 KGTTSTKKVFLILLKSFIGTGVLFLPNAFHNGGLFFSVSMLAFFGIYSYWCYYILVQA------K 352

  Fly   105 QRVPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVD--- 166
            ......||.   ::|||...||:|.:...:       |.....|....|::|.|::::..:|
Yeast   353 SSCGVSSFG---DIGLKLYGPWMRIIILFS-------LVITQVGFSGAYMIFTAKNLQAFLDNVF 407

  Fly   167 -------EYLVVWDVRIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYIFEEL- 223
                   .||:|:..     ||.:||..|.:|..|.|  | |..||..::.|..|::.:..:.|
Yeast   408 HVGVLPLSYLMVFQT-----IIFIPLSFIRNISKLSL--P-SLLANFFIMAGLVIVIIFTAKRLF 464

  Fly   224 -----PPLSERDPFVAAGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVL 283
                 .|.......:.|.:...|.||.:||.|.:|:|:.::::|..|:.|           .:||
Yeast   465 FDLMGTPAMGVVYGLNADRWTLFIGTAIFAFEGIGLIIPVQDSMRNPEKF-----------PLVL 518

  Fly   284 GLYVL--------LGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYALQGYVTAH 340
            .|.:|        :...||..||:..:..|.||:|||.|...::::|::|...:|..||.:....
Yeast   519 ALVILTATILFISIATLGYLAYGSNVQTVILLNLPQSNIFVNLIQLFYSIAIMLSTPLQLFPAIK 583

  Fly   341 ILWDKYLAKRFK------------ETRQTFYEL---------IFRAIIVLLTFGCAVAIPD-LSV 383
            |:.:|:..|..|            |.|....:|         ..|:|||::....|....| |..
Yeast   584 IIENKFFPKFTKIYVKHDDLTTRVELRPNSGKLNWKIKWLKNFIRSIIVIIVVSIAYFGSDNLDK 648

  Fly   384 FLSLVGSFCLSILGLIFPVLLQI---CVQYTEGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILD 445
            |:|::||.....|..|:|.:|.:   .:..|:|.. :|.|.:::.:|:.|||...:..:|.||..
Yeast   649 FVSVIGSLACIPLVYIYPSMLHLRGNSLPETKGEF-WRFKPMLDTILIFFGIASMLYTSYQSIFG 712

  Fly   446 I 446
            :
Yeast   713 V 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	104/409 (25%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	114/450 (25%)
AVT4	NP_014298.1	Aa_trans	295..711	CDD:279788	114/451 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I928
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I1099
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm9188
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
TreeFam	0	0.000	Not matched by this tool.
	8	7.860