DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1139 and AVT3

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_012776.1	Gene:	AVT3 / 853710	SGDID:	S000001629	Length:	692	Species:	Saccharomyces cerevisiae

Alignment Length:	468	Identity:	117/468 - (25%)
Similarity:	191/468 - (40%)	Gaps:	110/468 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 TKSANGSNDDYDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGS 85
            |:|....:.::..|.|:     ::..:.....||:.||||||.:|.||.:.|:          |.
Yeast   280 TESTQLVSREHGRHPHK-----SSTVKAVLLLLKSFVGTGVLFLPKAFHNGGW----------GF 329

  Fly    86 LALYCLHILIKCMYILCKRQRVPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGF--------- 141
            .|| |   |:.|..|       .|..|...:....|.|              |||:
Yeast   330 SAL-C---LLSCALI-------SYGCFVSLITTKDKVG--------------VDGYGDMGRILYG 369

  Fly   142 ----------LAFYHFGICCVYVVFIAESIKQLVDEYLVVWDVRIHMC-------IIIVPLLLIY 189
                      :|....|....|.||.|.:::...:.:..:....|.:.       :|.|||.|
Yeast   370 PKMKFAILSSIALSQIGFSAAYTVFTATNLQVFSENFFHLKPGSISLATYIFAQVLIFVPLSL-- 432

  Fly   190 SIKNLKLLAPFSSAANLLLLVGFGII----LYYI------FEELPPLSERDPFVAAGKLPTFFGT 244
             .:|:..|:..:..|:|.:|:|...:    :|||      .:.:...::.|       ...|.||
Yeast   433 -TRNIAKLSGTALIADLFILLGLVYVYVYSIYYIAVNGVASDTMLMFNKAD-------WSLFIGT 489

  Fly   245 VLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNI 309
            .:|..|.:|:::.|:|:|..||.| .|.  |::.|.||..:::..|...|..:|::.:..:.||.
Yeast   490 AIFTFEGIGLLIPIQESMKHPKHF-RPS--LSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNF 551

  Fly   310 PQSEIPAQVVKVFFAITTWISYALQGYVTAHIL--W-------DKYLAKRFKETRQTFYELIFRA 365
            ||.......|::.:|:...:|..||.:....||  |       .||      ..:..:.:..||.
Yeast   552 PQDTSYTLTVQLLYALAILLSTPLQLFPAIRILENWTFPSNASGKY------NPKVKWLKNYFRC 610

  Fly   366 IIVLLTFGCA-VAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIINLLLLC 429
            .||:||...| |...||..|:||||||....|..|:|.||........|..  |.:|:::|:::.
Yeast   611 AIVVLTSILAWVGANDLDKFVSLVGSFACIPLIYIYPPLLHYKASILSGTS--RARLLLDLIVIV 673

  Fly   430 FGIFGGVVGTYVS 442
            ||:   .|..|.|
Yeast   674 FGV---AVMAYTS 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	103/413 (25%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	113/447 (25%)
AVT3	NP_012776.1	Aa_trans	295..687	CDD:279788	114/453 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I928
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I1099
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm9188
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
TreeFam	0	0.000	Not matched by this tool.
	8	7.860