DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and AVT1

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_012534.1	Gene:	AVT1 / 853457	SGDID:	S000003761	Length:	602	Species:	Saccharomyces cerevisiae

Alignment Length:	465	Identity:	88/465 - (18%)
Similarity:	170/465 - (36%)	Gaps:	133/465 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCK 103
            |...:|..||..:.:...:|.|:||:|....:||:|.| |..|.|.:||.:|...|:.
Yeast   204 LAGQSTAPQTIFNSINVLIGIGLLALPLGLKYAGWVIG-LTMLAIFALATFCTAELLS------- 260

  Fly   104 RQRVPYVSFSQAMNLGLKQGPPWLRCL--APIAVPFVD-GFLAFYHFGICCV------------- 152
                                    |||  .|..:.:.| |:.||...|...:
Yeast   261 ------------------------RCLDTDPTLISYADLGYAAFGTKGRALISALFTLDLLGSGV 301

  Fly   153 -YVVFIAESIKQLVDEYLVVWDVRIHMCIIIVPLLLIYSI-KNLKLLAPFSSAANLLLLVGFGII 215
             .|:...:|:..|..:|...:...:...|:..|:.:..|: .|:.||...|:...:|::...|
Yeast   302 SLVILFGDSLNALFPQYSTTFFKIVSFFIVTPPVFIPLSVLSNISLLGILSTTGTVLVICCCG-- 364

  Fly   216 LYYIFEELPPLSERDPFVAAGKLPTFFGTVLFALE------AVGVILA----------IEENMAT 264
               :::...|          |.|.....|.::.::      ::|::.|          ::.:|..
Yeast   365 ---LYKSSSP----------GSLVNPMETSMWPIDLKHLCLSIGLLSACWGGHAVFPNLKTDMRH 416

  Fly   265 PKSFVGPC--------GILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSE-IPAQVVK 320
            |..| ..|        .:.:.|.:::          |:..:||..:..||.|:..:| .|..|..
Yeast   417 PDKF-KDCLKTTYKITSVTDIGTAVI----------GFLMFGNLVKDEITKNVLLTEGYPKFVYG 470

  Fly   321 VFFAITTWISYA---LQGYVTAHILWD------------KYLAKRFKETRQTFYELIFRAIIVLL 370
            :..|:.|.|..|   |.......:| |            ..:.:|..:..|.|..:....:.||:
Yeast   471 LISALMTIIPIAKTPLNARPIVSVL-DVLMNVQHIDEAASAIKRRAAKGLQVFNRIFINVVFVLI 534

  Fly   371 TFGCAVAIPDLSVFLSLVGS-FCLSILGLIFP--VLLQICVQYTEGYGPF-----RIKLIINLLL 427
                |:..|:....::.:|: .|.:|. ||.|  ..|::|....:   |:     .:.:.|:::|
Yeast   535 ----AINFPEFDKIIAFLGAGLCFTIC-LILPCWFYLRLCKTTIK---PWERVACHVTICISVVL 591

  Fly   428 LCFGIFGGVV 437
            ...|:...::
Yeast   592 STLGVGAAII 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	82/425 (19%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	87/462 (19%)
AVT1	NP_012534.1	Aa_trans	206..601	CDD:279788	87/461 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810