DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and Slc32a1

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_113970.1	Gene:	Slc32a1 / 83612	RGDID:	621402	Length:	525	Species:	Rattus norvegicus

Alignment Length:	480	Identity:	110/480 - (22%)
Similarity:	186/480 - (38%)	Gaps:	112/480 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ANGSNDDYDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLAL 88
            |.|:..::..|.    |...|.::...:...|..|..||.:|.|..|.||: |..|.:....:..
  Rat   101 AVGAGGEFGGHD----KPKITAWEAGWNVTNAIQGMFVLGLPYAILHGGYL-GLFLIIFAAVVCC 160

  Fly    89 YCLHILIKCMY-------ILCKRQRVPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYH 146
            |...|||.|:|       ::  |.|..||:.:.|             |.|| ..|.:.|
  Rat   161 YTGKILIACLYEENEDGEVV--RVRDSYVAIANA-------------CCAP-RFPTLGG------ 203

  Fly   147 FGICCVYVVFIAESIKQLVD--EYLVV------------------WDVRIHMCIIIVPLLLIYSI 191
                  .||.:|:.|:.::.  .|:||                  |.:     |....||....:
  Rat   204 ------RVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQKSWSI-----IATAVLLPCAFL 257

  Fly   192 KNLKLLAPFSSAANLL-LLVGFGIILYYIFEELPPLSERDPF-VAAGKLPTFFGTVLFALEAVGV 254
            ||||.::.||....|. .::...:|.|.:........|:..| :...|.|...|.::|:..:...
  Rat   258 KNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIF 322

  Fly   255 ILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVV 319
            :.::|.||..|..|.......:....::.||:.|:   .|..:.:|::..||.|:|.| |.| ||
  Rat   323 LPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALV---AYLTWADETKEVITDNLPGS-IRA-VV 382

  Fly   320 KVFFAITTWISYALQGYVTAHILWDKYLAKRFKETRQTFYE-------------LIFRAIIVLLT 371
            .:|......:||.|..:....:| :|.|   |:|..:.|:.             |..|..:|:.|
  Rat   383 NIFLVAKALLSYPLPFFAAVEVL-EKSL---FQEGSRAFFPACYGGDGRLKSWGLTLRCALVVFT 443

  Fly   372 FGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIINLLL-------LC 429
            ...|:.:|..::.:.|.||...:.|..:.|.|             |.::|:...||       :.
  Rat   444 LLMAIYVPHFALLMGLTGSLTGAGLCFLLPSL-------------FHLRLLWRKLLWHQVFFDVA 495

  Fly   430 FGIFGGV--VGTYVSILD-IIAVYK 451
            ..:.||:  |..:|..|: :|..|:
  Rat   496 IFVIGGICSVSGFVHSLEGLIEAYR 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	95/409 (23%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	103/452 (23%)
Slc32a1	NP_113970.1	Aa_trans	115..512	CDD:279788	103/452 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352533
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740