DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and Slc38a10

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	XP_006534347.1	Gene:	Slc38a10 / 72055	MGIID:	1919305	Length:	1111	Species:	Mus musculus

Alignment Length:	409	Identity:	82/409 - (20%)
Similarity:	166/409 - (40%)	Gaps:	96/409 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIK-CMYILCKRQR 106
            |:.:....:.:.:.||..||.||..|...|.|.|.|       |.::|..:..: ||::
Mouse     6 TSKWGLITNVVNSIVGVSVLTMPFCFKQCGIVLGAL-------LLVFCSWMTHQSCMFL------ 57

  Fly   107 VPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVDEYLVV 171
            |...|.|:.            |..|.:|      |.|:...|...|....|...:...:..|:|:
Mouse    58 VKSASLSKR------------RTYAGLA------FHAYGKAGKMLVETSMIGLMLGSCITFYVVI 104

  Fly   172 WDVRIHMCIIIVPLL-----------LIYSIKNLKLLAPFSSAANLLLLV----GFGIILYYIFE 221
            .|:..:   ...|||           |:::: :|.::.|.|...|::..:    ...::.|.:|.
Mouse   105 GDLGSN---FFAPLLGLQVTRTVRVFLLFAV-SLFIVLPLSLQRNMMASIQSFSAMALLFYTVFM 165

  Fly   222 ELPPLSERDPFVAAGK----------------LPTFFGTVLFALEAVGVILAIEENMATPKSFVG 270
            .:..||.....:.:|:                :|.|  .:.||.::  .:|...:::..| |...
Mouse   166 FVIVLSSLKHGLFSGQWLRQVSYIRWEGVFRCVPIF--GMSFACQS--QVLPTYDSLDEP-SVKT 225

  Fly   271 PCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYAL-- 333
            ...|..|.:::|...||::|||||..:.:.:.|::.::.|.:.: .::::|.|.::..:.:.:
Mouse   226 MSSIFASSLNVVTAFYVMVGFFGYVSFTDATTGNVLIHFPSNPV-TEMIRVGFVMSVAVGFPMMI 289

  Fly   334 ----QGYVTAHILWDKYLAKRFKETRQTFY------ELIFRAIIVLLTFGC---AVAIPDLSVFL 385
                |...|  :|:::      ::...||.      .|.|:.:.:.:.||.   .|.||::...|
Mouse   290 LPCRQALNT--LLFEQ------QQKDGTFAAGGYMPPLRFKVLTLSVVFGTMVGGVMIPNVETIL 346

  Fly   386 SLVGSFCLSILGLIFPVLL 404
            ...|:...|::..|.|.|:
Mouse   347 GFTGATMGSLICFICPALI 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	81/407 (20%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	82/409 (20%)
Slc38a10	XP_006534347.1	SLC5-6-like_sbd	6..381	CDD:382020	82/409 (20%)
		PTZ00121	<407..789	CDD:173412
		PTZ00449	<731..>991	CDD:185628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810