DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and slc38a9

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001073468.1	Gene:	slc38a9 / 562137	ZFINID:	ZDB-GENE-061013-597	Length:	549	Species:	Danio rerio

Alignment Length:	470	Identity:	88/470 - (18%)
Similarity:	156/470 - (33%)	Gaps:	159/470 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCK 103
            :|||  :..|........:||.:|::|.....||:..|.::.:::|.|.|||      |..:|..
Zfish   103 IKNP--SIVTIFAIWNTMMGTSILSIPWGIKQAGFTLGIIIIVLMGLLTLYC------CYRVLKS 159

  Fly   104 RQRVPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYHFGICCVY--VVFIAESIKQLVD 166
            .:.:|||..|.           |         .|.|  :..|:||....:  :||   |:..|:.
Zfish   160 TKSIPYVDTSD-----------W---------EFPD--VCKYYFGGFGKWSSLVF---SLVSLIG 199

  Fly   167 EYLVVW----------------------------------------DVRIH-------------- 177
            ..:|.|                                        ||..|
Zfish   200 AMVVYWVLMSNFLFNTGKFIFNYVHNVNTSDAFGTNGTERVICPYPDVDPHGNSSTSLYSGSDNS 264

  Fly   178 ------------------MCIIIVPLLLIYSIKNLKLLAPFS-----SAANLLLLV-------GF 212
                              :.::::|||   :.::....|.|:     |...|:.||       ||
Zfish   265 TGLEFDHWWSKTNTIPFYLILLLLPLL---NFRSASFFARFTFLGTISVIYLIFLVTYKAIQLGF 326

  Fly   213 GIILYYIFEELPPLSE-RDPFVAAGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILN 276
            .:..::....:..:.| |..|      |...|.:..|......|:.:.:|....::.|....:
Zfish   327 HLEFHWFDSSMFFVPEFRTLF------PQLSGVLTLAFFIHNCIITLMKNNKHQENNVRDLSL-- 383

  Fly   277 SGMSIVLGL-YVLLGFFGYWKYGNES------EGSITLNIPQSEIPAQVVKVF--FAITTWISYA 332
              ..:::|| |:.:|...:..:.:..      |.:...|.|.|:|...|.:.|  |.:||  .|.
Zfish   384 --AYLLVGLTYLYVGVLIFAAFPSPPLSKECIEPNFLDNFPSSDILVFVARTFLLFQMTT--VYP 444

  Fly   333 LQGYVTAHILWDKYLAKRFKETRQTFYELIFRAIIVLLTF--GCAVAI----PDLSVFLSLVGSF 391
            |.||:....|..:.....:..         |..:.||..|  |..|.:    |::...:...|:.
Zfish   445 LLGYLVRVQLMGQIFGNHYPG---------FLHVFVLNVFVVGAGVLMARFYPNIGSIIRYSGAL 500

  Fly   392 CLSILGLIFPVLLQI 406
            |...|..:.|.|:.:
Zfish   501 CGLALVFVLPSLIHM 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	87/466 (19%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	86/467 (18%)
slc38a9	NP_001073468.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		SdaC	100..549	CDD:223884	88/470 (19%)
		SLC5-6-like_sbd	110..538	CDD:294310	85/461 (18%)
		Important for arginine binding and amino acid transport. /evidence=ECO:0000269\|PubMed:29872228	117..122		1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594591
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830