DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1139 and slc36a4

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	XP_002664741.3	Gene:	slc36a4 / 504109	ZFINID:	ZDB-GENE-050309-239	Length:	488	Species:	Danio rerio

Alignment Length:	466	Identity:	147/466 - (31%)
Similarity:	246/466 - (52%)	Gaps:	43/466 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LELTTP-TKSANGSNDDYDPH-----QHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGY 73
            :|:.|| .:.|.|..::.|.:     ..:.|....|..||..|.||.::|||:|.:|.|..:||.
Zfish     9 MEVMTPLMEKAEGEEEEEDENVDGDEDSKHLPQGITFTQTLLHLLKGNIGTGLLGLPLAVKNAGI 73

  Fly    74 VNGTLLTLIIGSLALYCLHILIKCMYILCKRQRVPYVSFSQ----AMNLGLKQGPPWLRCLAPIA 134
            |.|.:..:::|.:.::|:|||:.|.:.|.:|.:...:.:|:    ||.|...|   .||..|...
Zfish    74 VLGPVSLVLMGVVCVHCMHILVNCSHQLSERLKRSPLGYSETVAAAMELSSSQ---CLRRSAHFG 135

  Fly   135 VPFVDGFLAFYHFGICCVYVVFIAESIKQLVD----------------------EYLVVWDVRIH 177
            ...|:.||.....|.|.||.||:||:|||:::                      ...|..|:|::
Zfish   136 RHLVNFFLVLTQLGFCSVYFVFLAENIKQVMEGTHMNSTAETVLLSSNSSEASVASSVAIDLRLY 200

  Fly   178 MCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYIFEELPPLSERDPFVAA-GKLPTF 241
            |..::..::::..|::|:.:|..|:.|||.:.:....|..||..:|.. ..|.|:.:. .|.|.|
Zfish   201 MVFLLPFIIVLTFIRDLRNMAALSAIANLCMAISLIFIFSYILNDLSD-PRRLPYASTWRKFPFF 264

  Fly   242 FGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSIT 306
            |||.:||.|.:||:|.:|..|..||.|.   ..||.||..::.|||.|...||.::.::.:||||
Zfish   265 FGTAIFAFEGIGVVLPLENQMREPKRFP---QALNIGMGFIIVLYVTLATLGYLRFRDDIKGSIT 326

  Fly   307 LNIPQSEIPAQVVKVFFAITTWISYALQGYVTAHILWDKYLAKRFKETRQTFYELIFRAIIVLLT 371
            ||:|......|:|||.::...::|:|:|.:|.|.||... :.:|.:::.:...:|..||::|.||
Zfish   327 LNLPHDSWSNQLVKVLYSFGVFVSFAVQFFVPAEILLPP-MCERVRKSWRRVADLSLRALLVCLT 390

  Fly   372 FGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIINLLLLCFGIFGGV 436
            ...||.||.|.:.:||||:...|.|.|:||.|:::....::...|  :.|:.::.:...|..|.:
Zfish   391 CVTAVLIPRLDLVISLVGAVSSSALALVFPPLVELIAFPSQPPPP--MLLLKDISIAALGFIGFL 453

  Fly   437 VGTYVSILDII 447
            .||||::.:||
Zfish   454 TGTYVTVEEII 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	130/394 (33%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	138/428 (32%)
slc36a4	XP_002664741.3	SLC5-6-like_sbd	42..460	CDD:294310	138/427 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.960