Protein Alignment acs and slc38a2

DIOPT Version :10

• Sequence 1: NP_647686.1
• Gene: acs / 38264
• FlyBaseID: FBgn0035300
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_001011056.1
• Gene: slc38a2 / 496466
• XenbaseID: XB-GENE-6258676
• Length: 493
• Species: Xenopus tropicalis
• Alignment Length: 542
• Identity: 108/542 - (19%)
• Similarity: 186/542 - (34%)
• Gaps: 185/542 - (34%)

  Fly    22 KSANGSNDD-----YDPHQH-------RELKN--------------------PTTNF-QTFAHFL 53
            :.::.||||     |.|..|       .:::|                    .||:| .:..:..
 Frog    13 EDSSNSNDDLNYSEYQPKNHPIKSHYDMDIENVHFLLEPTMSKKKCETEYLPGTTSFGMSVFNLS 77

  Fly    54 KASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIK-------CMYILCKRQRVPYVS 111
            .|.||:|:|.:..|.|:.|.....:|.:.:...:||.:|:|:|       .:|
 Frog    78 NAIVGSGILGLSYAMANTGIALFMILLVFVTVFSLYSIHLLLKTANEGGSLLY------------ 130

  Fly   112 FSQAMNLGLKQGPPWLRCLAPIAVP---FVDGFLAFYHFGICCVYVVFIAES----IKQLVD--- 166
                ..||||          ...:|   ...|.:...:.|....|:..:...    ||.|:|
 Frog   131 ----EQLGLK----------AFGIPGKLAASGSVTLQNIGAMSSYLYIVKYELPLVIKALMDIKE 181

  Fly   167 ---------EYLVVWDVRIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYIFEE 222
                     :|||:    :....||:||.|   ::||..|. ::|..:.|.:|.|.|::.|...|
 Frog   182 SNGEWYLNGDYLVI----MVSLAIILPLSL---LRNLGYLG-YTSGFSPLCMVFFLIVVIYKKFE 238

  Fly   223 LP-PL-----------------SERDPFVAAGKLPTFFGTVLFALEAV-------GVILAIEENM 262
            :| ||                 :|.|..:...|...|....::|:..:       ..:|.|.:.:
 Frog   239 IPCPLEAMNMTSNSSSHDHMAHNETDDEMCKPKYFVFNSQTVYAVPILTFSFVCHPAVLPIYQEL 303

  Fly   263 ATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEG------------------------ 303
             ..:|......:.|.....:..:|:|...|||..:.::.|.
 Frog   304 -KGRSRRRMMNVSNVSFFAMFIMYLLAALFGYLTFYSKVEPELLHTYSKVFGAGVIFVVVRLAVL 367

  Fly   304 -SITLNIPQSEIP--AQVVKVF-----FAITTWISYALQGYVTAHILWDKYLAKRFKETRQTFYE 360
             ::||.:|....|  :.:.::|     ||   ||         .|||             .||..
 Frog   368 MAVTLTVPIVIFPIRSSLNELFCSGKDFA---WI---------RHIL-------------ITFLI 407

  Fly   361 LIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIINL 425
            |.|..::|:.       :|.:......:|:...::|..|.|....|.:...|...  .::.|..|
 Frog   408 LAFTNVLVIF-------VPTIRDIFGFIGASAAAMLVFILPSAFYIRLVKKESMK--SVQKIGAL 463

  Fly   426 LLLCFGIFGGVVGTYVSILDII 447
            |.|..||...:....:.|||.|
 Frog   464 LFLIGGIIVMIGSMTLIILDWI 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
acs	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:444915	96/485 (20%)
slc38a2	NP_001011056.1	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..92		16/78 (21%)
		SLC5-6-like_sbd	65..482	CDD:444915	96/485 (20%)