DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1139 and CG30394

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster

Alignment Length:	448	Identity:	101/448 - (22%)
Similarity:	179/448 - (39%)	Gaps:	92/448 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 AHFL---KASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKRQRVPYVS 111
            ||.:   .:.:|.|:||||..|...|.:...:|.::...:...|.|.|||...:..:|      |
  Fly     6 AHVMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSLLTRRR------S 64

  Fly   112 FSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVDEYLVVWDVRI 176
            |..   |||.......:.|..:.   :.|:|    .|.|..|.|.:.:...|::.:...: ||..
  Fly    65 FEM---LGLHAFGTSGKLLVELC---IIGYL----IGTCITYFVVVGDLGPQIIAKIFAL-DVAD 118

  Fly   177 HM-----------CIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGI--ILYYIFEELPPLSE 228
            |:           .:.||||.::.::.:|..:...|        :||.:  ||..:.|..|.::.
  Fly   119 HLHLRSLVMVVVTVVCIVPLGMLRNVDSLSAVCTAS--------IGFYVCLILKIVLEAQPHITA 175

  Fly   229 RD---------PFVAAGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLG 284
            .|         |......||.|...:...::...|..:| .|.:..|.    .||:.:...|...
  Fly   176 NDWTEKVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESI-NNQSLDKL----NGIVRNATWICTF 235

  Fly   285 LYVLLGFFGYWKYGNES-EGSITLNIPQSEIPAQVVKVFFAITTWISYALQGYVTAHILWDKYLA 348
            :|:.:|||||..:...: .|:|.:|:..| ..:.::|:.|.::...|:.|..:.....|:.....
  Fly   236 VYISVGFFGYVAFCTHTFSGNILVNLSTS-FGSDIIKIGFVLSIAFSFPLVIFPCRASLYSLLYR 299

  Fly   349 KRFKETRQTFYELIFRAI---IVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQY 410
            |...|:.....|..||.|   ||:.:...|:.||.:.:.:.||||          .:.:.||:.:
  Fly   300 KGHTESSSYIPEQRFRFITIFIVVFSLCVALVIPSVELIIGLVGS----------TIGVAICIMF 354

  Fly   411 TEGYGPFRIKLI----INLLLLCFGIFGG----VVGTYVSI-----------LDIIAV 449
            ..  ..|| |:|    :...|..|....|    ::|||.::           .|::|:
  Fly   355 PA--SSFR-KIIKKESMERTLAQFVFVSGFLLMILGTYANLSAIDEKSSGPEFDMVAI 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	87/382 (23%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	99/441 (22%)
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	97/427 (23%)
		SLC5-6-like_sbd	8..390	CDD:294310	96/425 (23%)
		DUF4775	<394..652	CDD:292620	2/16 (13%)
		YukC	<561..660	CDD:295067
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468292
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840