DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1139 and slc38a6

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001018308.1	Gene:	slc38a6 / 336741	ZFINID:	ZDB-GENE-050522-51	Length:	449	Species:	Danio rerio

Alignment Length:	519	Identity:	98/519 - (18%)
Similarity:	184/519 - (35%)	Gaps:	178/519 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 NGSN------DDYDPHQHRELKNPT---------TNFQTFA-HFLKASVGTGVLAMPSAFAHAGY 73
            ||:|      .:|:|....|.:.|.         ::|.:.| :.:.|.:|:|:|.:..|.|:.|.
Zfish     4 NGANHSIQTVSEYEPIGEDEERTPLLPQGVQTRGSSFMSSAFNLMNAIMGSGILGLSYAMANTGT 68

  Fly    74 VNGTLLTLIIGSLALYCLHILIKCMYILCKRQRV-PYVSFSQ----------------AMNLG-- 119
            |..::|.|::.|||.|.:|:|:    :||.:..: .|.:..:                ..|:|
Zfish    69 VGFSILLLMVASLAAYSIHLLL----LLCDKTGINSYEALGEKALNRPGKILVACTILIQNIGAM 129

  Fly   120 ------LKQGPP----------------WLR------------CLAPIAVPFVDGFLAFYHFGIC 150
                  ||...|                |..            .:.|:|:....|||. |...|.
Zfish   130 SSYLFILKTELPAAIIGFMRSDSETSGKWFENGVTLLILVTVIIVLPLALLPKIGFLG-YTSSIA 193

  Fly   151 CVYVVF--IAESIKQLVDEYLVVWDVRIHMCIIIVPLLLIYSIKNLKLLAPF----SSAANLLLL 209
            .::::|  :...:|:        |.:   .|.:.:...|..|:...:..|..    |.:|..:..
Zfish   194 FLFMLFFTVVVVVKK--------WSI---PCPLPINSTLSLSLNTSECTAQLFVISSKSAYAVPT 247

  Fly   210 VGFGII----LYYIFEEL-PPLSERDPFVAAGKLPTFFGTVLFALEA----------VGVILAIE 259
            :.|..:    ::.|:.|| .|...|  ...|..:..|...|::.:.|          ||..|.:.
Zfish   248 MAFSFLCHTAVFPIYCELHRPTKRR--MQRATNVSIFLSFVVYLISALFGYLTFYSHVGSELLLA 310

  Fly   260 ENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFA 324
            .|...|:..:    :::..::|:|                    ::.|.:|....||:  |....
Zfish   311 YNTYLPRDIL----VMSVRLAILL--------------------AVLLTVPLIHFPAR--KAVLM 349

  Fly   325 IT------TWISYALQGYVTAHILWDKYLAKRFKETRQTFYELIFRAIIVLLTFGCAVAIPDLSV 383
            :.      :|:|:.|..:                          |...:|||   .|:.:||:..
Zfish   350 LCRGEREFSWLSHTLSCF--------------------------FILTLVLL---LAIFVPDIKN 385

  Fly   384 FLSLVGSFCLSILGLIFP--VLLQICVQYTEGYGPFR-IKLIINLLLLCFGIFGGVVGTYVSIL 444
            ...:|||...:.|..::|  ..|:|..:      |.| ...:..:.||..|:..||:...|.|:
Zfish   386 VFGVVGSTTSTCLLFVYPGMFFLRISSE------PIRSFNSVGAVFLLVIGLVVGVLSLSVIIV 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	82/459 (18%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	91/494 (18%)
slc38a6	NP_001018308.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25		6/20 (30%)
		SLC5-6-like_sbd	36..443	CDD:294310	90/485 (19%)
		SdaC	37..442	CDD:223884	90/483 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594513
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750