DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and Slc36a4

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001101597.1	Gene:	Slc36a4 / 315439	RGDID:	1311528	Length:	500	Species:	Rattus norvegicus

Alignment Length:	457	Identity:	147/457 - (32%)
Similarity:	237/457 - (51%)	Gaps:	47/457 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 NGSNDD--------YDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTL 81
            :||:|:        ...|...:.::..:..||..|.||.::|||:|.:|.|..:||.|.|.:..:
  Rat    30 DGSSDEEQEQTLLPMQKHYQLDGQHGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLV 94

  Fly    82 IIGSLALYCLHILIKCMYILCKRQRVPYVSFSQAMNLGLKQGPPWLRCLAPIAV---PFVDGFLA 143
            .||.::::|:|||::|.:.||:|.:...:.:|..::..: :..|| .||...|.   ..||.||.
  Rat    95 FIGIISVHCMHILVRCSHFLCQRFKKSTLGYSDTVSFAM-EASPW-SCLQRQAAWGRSVVDFFLV 157

  Fly   144 FYHFGICCVYVVFIAESIKQ----LVDEYLVV--------------WDVRIHMCIIIVPLLLIYS 190
            ....|.|.||:||:||::||    |::..:||              .|:|::|...:..|:|:..
  Rat   158 ITQLGFCSVYIVFLAENVKQVHEGLLETTVVVSNSSDLSQVCERRSVDLRVYMLCFLPLLILLVF 222

  Fly   191 IKNLKLLAPFSSAANLLLLVGFGIILYYIFEELPPLSERDPF---VAAG--KLPTFFGTVLFALE 250
            |:.||.|...|..||:.:.....||..|:...:|     ||.   :.||  |.|.||||.:||.|
  Rat   223 IRELKSLFVLSFLANISMAASLVIIYQYVVRSMP-----DPHNLPIVAGWKKYPLFFGTAVFAFE 282

  Fly   251 AVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIP 315
            .:||:|.:|..|...|.|.   ..||.||:||..||:.|...||..:.:|.:||||||:||....
  Rat   283 GIGVVLPLENQMRESKRFP---QALNIGMAIVTVLYISLATLGYMCFRDEIKGSITLNLPQDMWL 344

  Fly   316 AQVVKVFFAITTWISYALQGYVTAHILWDKYLAKRFKETRQTFYELIFRAIIVLLTFGCAVAIPD 380
            .|.||:.::...:::|::|.||.|.|:.....| |.....:...:...|:::|.:|...||.||.
  Rat   345 YQSVKILYSFGIFVTYSIQFYVPAEIIIPAVTA-RLHAKWKCICDFGIRSLLVSITCAGAVLIPR 408

  Fly   381 LSVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILD 445
            |.:.:|.||:...|.|.||.|.|::|.....:.|..:.:  :.|:.:...|..|.::||||::.:
  Rat   409 LDIVISFVGAVSSSTLALILPPLVEILTFSKDHYNVWMV--LKNISIAFTGFVGFLLGTYVTVEE 471

  Fly   446 II 447
            ||
  Rat   472 II 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	131/393 (33%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	141/427 (33%)
Slc36a4	NP_001101597.1	SLC5-6-like_sbd	54..469	CDD:294310	141/427 (33%)
Slc36a4	NP_001101597.1	PotE	<223..477	CDD:223605	90/262 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352599
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.860