Protein Alignment acs and Slc38a9

DIOPT Version :10

• Sequence 1: NP_647686.1
• Gene: acs / 38264
• FlyBaseID: FBgn0035300
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_001030328.1
• Gene: Slc38a9 / 310091
• RGDID: 1311881
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 105/563 - (18%)
• Similarity: 183/563 - (32%)
• Gaps: 192/563 - (34%)

  Fly     1 MNDDIKTVTVYPTTL--------ELTTPTKSANGSNDDYDPHQHR-----------ELKNPT--- 43
            :||.|:.|:.:...:        .||||...|..:.|...|....           :||:.|
  Rat    49 VNDVIQKVSDHAAAMNKRIHYYSRLTTPADKALIAPDHVVPAPEECYVYSPLGSAYKLKSYTEGY 113

  Fly    44 ---TNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYIL---- 101
               |:..|........:||.:|::|.....||:..|..:.:::|.|.|||.:.::|...::
  Rat   114 RKNTSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIVLMGLLTLYCCYRVVKSRSMIVTSD 178

  Fly   102 ---------CKRQRVPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFI 157
                     ||..   :.||.|           |...|.
  Rat   179 TTTWEYPDVCKHY---FGSFGQ-----------WSSLLF-------------------------- 203

  Fly   158 AESIKQLVDEYLVVWDVRIHMCIIIVPLL---------LIYSIKNL-KLLAPFSSAANLLLLVGF 212
              |:..|:...:|.|       :::...|         .|:.|.:. .:|:..:|:..:....|.
  Rat   204 --SLVSLIGAMIVYW-------VLMSNFLFNTGKFIFNFIHHINDTDTVLSTNNSSPVICPSAGS 259

  Fly   213 G-----IILYY-------IFEELPPLSERDPFVAAG--------KLPTFF------GTV------ 245
            |     .:::|       :||.....|:..||...|        |.|:||      |||
  Rat   260 GHPDNSSMIFYNSDTEVRLFERWWDKSKTVPFYLIGLLLPLLNFKSPSFFSKFNILGTVSVLYLI 324

  Fly   246 -LFALEAVGVILAIEENMATPKSFVGP---------CGILNSGMSI------------------- 281
             :..|:|:.:...:|.:...|..|..|         .|:|.....|
  Rat   325 FIVTLKAIRLGFHLEFHWFAPTEFFVPEIRAQFPQLTGVLTLAFFIHNCIITLLKNNKNQENNVR 389

  Fly   282 --------VLGLYVLLGFFGYWKYGNES------EGSITLNIPQSEIPAQVVKVFFAITTWISYA 332
                    |...|:.:|...:..:.:..      |.:...|.|.|:..:.:.::.........|.
  Rat   390 DLCIAYMLVTLTYLYIGVLVFASFPSPPLPKDCIEQNFLDNFPSSDTLSFIARICLLFQMMTVYP 454

  Fly   333 LQGYVT-----AHILWDKYLAKRFKETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFC 392
            |.||:.     .||..|.|        ...|:.||...|||......|...|::...:...|:.|
  Rat   455 LLGYLARVQLLGHIFGDIY--------PSIFHVLILNLIIVGAGVTMACFYPNIGGIIRYSGAAC 511

  Fly   393 LSILGLIFPVLLQICVQYTEGYGPFRI---KLIINLLLLCFGI 432
            ......|:|.|:.|..|:.|.    |:   ||:.:::::..|:
  Rat   512 GLAFVFIYPSLIYILSQHQEE----RLTWPKLVFHIIIIILGL 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
acs	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:444915	92/503 (18%)
Slc38a9	NP_001030328.1	SLC5-6-like_sbd	114..555	CDD:444915	91/498 (18%)
		Important for arginine binding and amino acid transport. /evidence=ECO:0000250|UniProtKB:Q08BA4	128..133		1/4 (25%)
		CARC motif. /evidence=ECO:0000250|UniProtKB:Q8NBW4	442..452		0/9 (0%)
		CRAC motif. /evidence=ECO:0000250|UniProtKB:Q8NBW4	455..461		3/5 (60%)