DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and Slc36a3

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001019935.1	Gene:	Slc36a3 / 303148	RGDID:	1309092	Length:	477	Species:	Rattus norvegicus

Alignment Length:	442	Identity:	149/442 - (33%)
Similarity:	236/442 - (53%)	Gaps:	27/442 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 SANGSNDDYDPHQHRELKNPTTNF-QTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSL 86
            |::.||:.....:....|.....| |.|.|.||:::|||.|.:|.|..:||.:.|.:..|.||:|
  Rat    29 SSSSSNNTVSSKKKPRRKADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGAL 93

  Fly    87 ALYCLHILIKCMYILCKRQRVPYVSFSQAMNLGLKQGP-PWLRCLAPIAVPFVDGFLAFYHFGIC 150
            .::|:.||:.|...|..|.:..:|::.:.....|:..| ||||..:......|...|.....|.|
  Rat    94 TVHCMDILLNCACHLTSRLQRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFC 158

  Fly   151 CVYVVFIAESIKQLVDE------------YLV---VWDVRIHMCIIIVPLLLIYSIKNLKLLAPF 200
            .||.:|:|::::|:|:|            .||   :.|.|.:|..|:..|:|:..::|.::|:.|
  Rat   159 SVYFMFMADNLQQIVEEAHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLVQNPQVLSIF 223

  Fly   201 SSAANLLLLVGFGIILYYIFEELPPLSERDPFVAAGK-LPTFFGTVLFALEAVGVILAIEENMAT 264
            |:.|.:..|....:|..|:. ::|..|.. |.||:.| ...||||.:|..|.||::|.::..|.:
  Rat   224 STLATITTLSSLALIFEYLI-QIPHHSHL-PLVASWKTFLLFFGTAIFTFEGVGMVLPLKSQMKS 286

  Fly   265 PKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWI 329
            |:.|.   .:|..|||.|:.||:.||..||.|:|.:::.|||||:|...: .|.||:.:::..:.
  Rat   287 PQQFP---AVLYLGMSFVIFLYICLGTLGYMKFGADTQASITLNLPNCWL-YQSVKLMYSVGIFF 347

  Fly   330 SYALQGYVTAHILWDKYLAKRFKETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLS 394
            :||||.:|.|.|: ..|:..|..|....|.:|..||.:|.||...||.||.|.:.:|||||...|
  Rat   348 TYALQFHVPAEII-VPYVVSRASENWALFIDLTVRAALVCLTCFSAVLIPRLDLVISLVGSVSSS 411

  Fly   395 ILGLIFPVLLQICVQYTEGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILDI 446
            .|.||.|.||:|...|:|......|...|.:.:|  |:.|.|:|||.::.::
  Rat   412 ALALIIPPLLEIATFYSENISCTTIAKDIMISIL--GLLGCVLGTYQALYEM 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	132/385 (34%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	145/419 (35%)
Slc36a3	NP_001019935.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42		3/12 (25%)
Slc36a3	NP_001019935.1	SLC5-6-like_sbd	52..458	CDD:294310	145/414 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352620
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.860