DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and Slc38a2

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	XP_006242344.1	Gene:	Slc38a2 / 29642	RGDID:	69420	Length:	535	Species:	Rattus norvegicus

Alignment Length:	533	Identity:	102/533 - (19%)
Similarity:	184/533 - (34%)	Gaps:	164/533 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PTKSA--NGSNDDYDPHQHRELKNP--------------TTNF-QTFAHFLKASVGTGVLAMPSA 67
            |||.|  .....|.||.....|...              ||:| .:..:...|.||:|:|.:..|
  Rat    31 PTKQAALKSHYVDVDPENQNFLLESNLGKKKYETDFHPGTTSFGMSVFNLSNAIVGSGILGLSYA 95

  Fly    68 FAHAGYVNGTLLTLIIGSLALYCLHILIK-------CMYILCKRQRVPYVSFSQAMNLGLKQGPP 125
            .|:.|.....:|...:...:||.:|:|:|       .:|     :::.:.::..|..|.
  Rat    96 MANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLY-----EQLGHKAYGLAGKLA------ 149

  Fly   126 WLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAES----IKQLVD------------EYLVVWDV 174
                        ..|.:...:.|....|:..:...    ||.|::            :|||:
  Rat   150 ------------ASGSITMQNIGAMSSYLFIVKYELPLVIKALMNIEDTNGLWYLNGDYLVL--- 199

  Fly   175 RIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGF----GIILYYIFE-ELPPLSERDPFVA 234
             :...::|:||.|   ::||..|. ::|..:||.::.|    |::::...: .|..||.....:.
  Rat   200 -LVSFVLILPLSL---LRNLGYLG-YTSGLSLLCMIFFLIVVGVVVFVCRKCILKALSGHPALLT 259

  Fly   235 AG-----------KLPTFFGTVLFALEAVG------VILAIEENMAT-----PKSFVGPCGILNS 277
            :.           ::|......|.|.|.|.      .:.|:..|...     |:.|     |.||
  Rat   260 SAIFCCQVICKKFQIPCPVEVALMANETVNGTFTQVALAALASNSTAADTCRPRYF-----IFNS 319

  Fly   278 G---------------------------------MSI-------VLGLYVLLGFFGYWKYGNESE 302
            .                                 |::       :..:|:|...|||..:....|
  Rat   320 QTVYAVPILTFSFVCHPAVLPIYEELKSRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVE 384

  Fly   303 GSITLN---IPQSEIPAQVVK--VFFAITTWIS---YALQGYVTAHILWDKYLAKRFKETRQTFY 359
            ..:...   |..::|...||:  |..|:|..:.   :.::..|| |:|........|:.:..|..
  Rat   385 SELLHTYSAIVGTDILLLVVRLAVLVAVTLTVPVVIFPIRSSVT-HLLCPTKEFSWFRHSVITVT 448

  Fly   360 ELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIIN 424
            .|.|..::|:.       :|.:......:|:...::|..|.|....|.:...|   |.|  .:..
  Rat   449 ILAFTNLLVIF-------VPTIRDIFGFIGASAAAMLIFILPSAFYIKLVKKE---PMR--SVQK 501

  Fly   425 LLLLCFGIFGGVV 437
            :..|||.:.|.||
  Rat   502 IGALCFLLSGVVV 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	85/480 (18%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	94/509 (18%)
Slc38a2	XP_006242344.1	SdaC	64..516	CDD:223884	94/500 (19%)
Slc38a2	XP_006242344.1	SLC5-6-like_sbd	69..518	CDD:294310	94/495 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840