DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and slc-36.1

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_499743.2	Gene:	slc-36.1 / 259544	WormBaseID:	WBGene00012804	Length:	455	Species:	Caenorhabditis elegans

Alignment Length:	451	Identity:	149/451 - (33%)
Similarity:	246/451 - (54%)	Gaps:	27/451 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PTTLELTTPTKSANGSNDDYDPHQHR-ELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVN 75
            |...|:.||.:  |..::|....|.| ..:|..|..|.|.|.:||.:|||:|::|.||.|:|...
Worm    19 PGDTEVQTPRR--NTVSEDTSLFQDRLPTENSLTPEQAFIHMVKAMLGTGLLSLPLAFKHSGLFL 81

  Fly    76 GTLLTLIIGSLALYCLHILIKCMYILCKRQRVPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDG 140
            |.:||::|..:.|||:..::...:.:|.|.....:.::..|...::.||||::.........|:.
Worm    82 GLILTVLICLICLYCMRQVVFAAHFVCNRNGRDLIDYANIMRGAVEMGPPWIKRNGYFFKQLVNV 146

  Fly   141 FLAFYHFGICCVYVVFIAESIKQLVDEYL------VVWDVRIHMCIIIVPLLLIYSIKNLKLLAP 199
            .:.....|.||||.||:|::::...:...      .||     |.::::|:|.|.||:.|.:|||
Worm   147 NMFISQLGFCCVYFVFMADNLEDFFNNNTSIHLSKAVW-----MLLLLIPMLSICSIRRLSILAP 206

  Fly   200 FSSAANLLLLVGFGIILYYIFEELPPLSERDPFVAAGKLPTFFGTVLFALEAVGVILAIEENMAT 264
            |:.|||::.:|...::|::...:|.|:|....|..|..||.|||||:||.|.|.||:.||..|.:
Worm   207 FAMAANVVYVVAVAVVLFFFLSDLRPISSLPWFGKATDLPLFFGTVMFAFEGVAVIMPIENRMQS 271

  Fly   265 PKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWI 329
            |.:|:...|:|||...:||.::.:.||:||...||:.:.:.|||:|.:.. .|.:|:.|.....|
Worm   272 PHAFISWNGVLNSSCLVVLAIFSVTGFYGYLSLGNDVKDTATLNLPMTPF-YQTIKLMFVACIMI 335

  Fly   330 SYALQGYVTAHILWDKYLAKRFKETRQTFYELIFRAIIVLLTFGCAVA--IPDLSVFLSLVGSFC 392
            ||.||.||....: :|::.::....:||.|..|.|...|:||  ||:|  ||.|::|:||:|:|.
Worm   336 SYPLQFYVPMERI-EKWITRKIPVDKQTLYIYIARYSGVILT--CAIAELIPHLALFISLIGAFS 397

  Fly   393 LSILGLIFPVLLQICVQYTEGYGPFRIKL---IINLLLLCFGIFGGVVGTYVSILDIIAVY 450
            .:.:.|:||.    |::....|....:..   |.|::||.|...|...|||.::::|...:
Worm   398 GASMALLFPP----CIELLTSYAKNELSTGLWIKNIVLLTFAFIGFTTGTYSALIEIAKTF 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	130/376 (35%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	139/412 (34%)
slc-36.1	NP_499743.2	SLC5-6-like_sbd	50..445	CDD:382020	138/407 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166170
Domainoid	1	1.000	277	1.000	Domainoid score	I909
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	282	1.000	Inparanoid score	I1740
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm4749
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.910