DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1139 and Slc36a2

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_694810.2	Gene:	Slc36a2 / 246049	MGIID:	1891430	Length:	478	Species:	Mus musculus

Alignment Length:	464	Identity:	164/464 - (35%)
Similarity:	249/464 - (53%)	Gaps:	44/464 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PTTLELTTPTKS--------ANGSNDDYDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAF 68
            |..|:|....|.        ||||:.:    ..::.|. .|.|||..|.:|.::|||:|.:|.|.
Mouse    15 PLNLDLPESAKKLQSQDPSPANGSSSE----SSKKTKG-ITGFQTLVHLVKGNMGTGILGLPLAV 74

  Fly    69 AHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKRQRVPYVSFSQAMNLGLKQGP-PWLRCLAP 132
            .:||.:.|.|..|::|.:|.:|:|||::|....|.|...|::.:...:..||...| .||:..|.
Mouse    75 KNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRLNKPFMDYGDTVMHGLAFSPNAWLQNHAH 139

  Fly   133 IAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVD------------EYLVV---WDVRIHMCIII 182
            .....|..||.....|.||||:||:|:::||:|:            |.:|:   .|.|::|...:
Mouse   140 WGRRVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETVVLTPTMDSRLYMLSFL 204

  Fly   183 VPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYIFEELPPLSERDPFVAAGK-LPTFFGTVL 246
            ..|.|:..::||::|..||..||:.:||...||..||.:|:|..|:. |.||:.| .|.||||.:
Mouse   205 PVLGLLVFVRNLRVLTIFSLLANISMLVSLVIIAQYIIQEIPDASQL-PLVASWKTYPLFFGTAI 268

  Fly   247 FALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQ 311
            |:.|::||:|.:|..|...:.|  |. ||:.||||:..||:.:|..||.::|::.:.|||||:|.
Mouse   269 FSFESIGVVLPLENKMKDARGF--PT-ILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLPN 330

  Fly   312 SEIPAQVVKVFFAITTWISYALQGYVTAHI---LWDKYLAKRFKETRQTFYELIFRAIIVLLTFG 373
            ..: .|.||:.:.:....:||||.||.|.|   |....::||:...    .:|..|..:|.||..
Mouse   331 CWL-YQSVKLLYVVGILCTYALQFYVPAEIIIPLAVSQVSKRWALP----VDLSIRLALVCLTCM 390

  Fly   374 CAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIINLLLLCFGIFGGVVG 438
            .|:.||.|.:.||||||...|.|.||.|.||::...|.||..|..:..  :.|:...|..|.|||
Mouse   391 LAILIPRLDLVLSLVGSVSSSALALIIPPLLEVVTYYGEGISPLTVTK--DALISILGFMGFVVG 453

  Fly   439 TYVSILDII 447
            ||.::.::|
Mouse   454 TYQALDELI 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	141/387 (36%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	154/421 (37%)
Slc36a2	NP_694810.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46		8/34 (24%)
Slc36a2	NP_694810.2	SLC5-6-like_sbd	48..458	CDD:294310	154/421 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849005
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.860