Protein Alignment acs and SLC36A1

DIOPT Version :10

• Sequence 1: NP_647686.1
• Gene: acs / 38264
• FlyBaseID: FBgn0035300
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: XP_047272876.1
• Gene: SLC36A1 / 206358
• HGNCID: 18761
• Length: 507
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 164/456 - (35%)
• Similarity: 250/456 - (54%)
• Gaps: 28/456 - (6%)

  Fly    11 YPTTLELTTPTKSANGSNDDYDPHQHREL--KNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGY 73
            |.:| :::.....:.|.|:...|..::..  .|.||.|||..|.||.::|||:|.:|.|..:||.
Human    45 YSST-DVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGI 108

  Fly    74 VNGTLLTLIIGSLALYCLHILIKCMYILCKRQRVPYVSFSQAMNLGLKQGP-PWLRCLAPIAVPF 137
            |.|.:..||||.:|::|:.||:||.:..|:|....:|.:...:..||:..| .|||..|......
Human   109 VMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRV 173

  Fly   138 VDGFLAFYHFGICCVYVVFIAESIKQLVD------------EYLVV---WDVRIHMCIIIVPLLL 187
            ||.||.....|.||||.||:|::.||:::            |.:::   .|.|::|...:..|:|
Human   174 VDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVL 238

  Fly   188 IYSIKNLKLLAPFSSAANLLLLVGFGIILYYIFEELPPLSERDPFVAAGK-LPTFFGTVLFALEA 251
            :..|:||:.|:.||..||:.:||...:|..:|.:.:|..|.. |.||..| .|.||||.:|:.|.
Human   239 LVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHL-PLVAPWKTYPLFFGTAIFSFEG 302

  Fly   252 VGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPA 316
            :|::|.:|..|..|:.|  |. ||..||.||..||:.||..||.::|...:||||||:|...: .
Human   303 IGMVLPLENKMKDPRKF--PL-ILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWL-Y 363

  Fly   317 QVVKVFFAITTWISYALQGYVTAHILWDKYLAKRFKETRQTFYELIFRAIIVLLTFGCAVAIPDL 381
            |.||:.::|..:.:||||.||.|.|: ..:...|..|..:...:|..|.::|.||...|:.||.|
Human   364 QSVKLLYSIGIFFTYALQFYVPAEII-IPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRL 427

  Fly   382 SVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILDI 446
            .:.:|||||...|.|.||.|.||::...|:||..|  :.:..:.|:...|..|.|||||.::.::
Human   428 DLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSP--LTIFKDALISILGFVGFVVGTYEALYEL 490

  Fly   447 I 447
            |
Human   491 I 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
acs	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:444915	157/418 (38%)
SLC36A1	XP_047272876.1	SLC5-6-like_sbd	78..484	CDD:444915	155/413 (38%)