DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1139 and Slc38a5

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	XP_008771290.2	Gene:	Slc38a5 / 192208	RGDID:	620702	Length:	479	Species:	Rattus norvegicus

Alignment Length:	479	Identity:	94/479 - (19%)
Similarity:	176/479 - (36%)	Gaps:	85/479 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNDDIKT--VTVYPTTLELTTPTKSANGSNDDYDPHQHRELKNPTTNFQTFAHFLKASVGTGVLA 63
            ||..:.|  ...|....|...||  .:|......|.|..:.:..|:...:..:...|.:|:|:|.
  Rat    16 MNGTLSTGAAAGYRQEREGFLPT--THGPAPGRKPVQFLDFEGKTSFGMSVFNLSNAIMGSGILG 78

  Fly    64 MPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKRQRVPYVSFSQAMNLGLKQGPPWLR 128
            :..|.||.|.:....|.|.|..|:.|.:|:|:.|..::..|   .|....|             |
  Rat    79 LAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIR---AYEQLGQ-------------R 127

  Fly   129 CLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVDEYLVV-----WDVRIHMCIIIVPLLLI 188
            ...|.....|...:..::.|....|:..|...:..::..:|.:     |.::.::.||:|.||:|
  Rat   128 AFGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHMDPEGDWFLKGNLLIILVSLLII 192

  Fly   189 YSIKNLKLLA--PFSSAANLLLLVGFGI-ILYYIFEELPPLSERDPFVAAGKLPTFFGTVLFALE 250
            ..:..:|.|.  .::|:.:|..::.|.| ::|..|:....:|..|..|.:...|    ...|...
  Rat   193 LPLALMKHLGYLGYTSSLSLTCMLFFLISVIYKKFQLGCVVSHNDTVVESEPAP----LQAFNSS 253

  Fly   251 AVGVILAIEENMA--TP-KSFVGPC--------------------GILNSGMSIVLGLYVLLGFF 292
            ....:..::..|:  .| .:|...|                    .:.|..:..:..:|.|...|
  Rat   254 CEAKLFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCCPTQRRMQAVANMSIGAMFIMYGLTATF 318

  Fly   293 GYWKYGNESEGSITLNIPQSEIPAQVVK--VFFAITTW-------ISYALQGYVTAHILWDKYLA 348
            ||..:.:..:..:.....|.::....|:  |..|:|..       |..|||..:        :.:
  Rat   319 GYLTFYSTVKAEMLEMYTQEDLLILCVRLAVLLAVTLTVPVVLFPIRRALQQLL--------FPS 375

  Fly   349 KRFKETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYTEG 413
            |.|...|.....||...::.:|    .:.:|.:......:||.....|..|.|.:..:.:.
  Rat   376 KAFSWPRHVAIALILLILVNIL----VICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIV---- 432

  Fly   414 YGPFRIKLIIN---LLLLCFGIFG 434
              |..::.:.:   :..||||:.|
  Rat   433 --PADMEPLFSWPKIQALCFGVLG 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	78/407 (19%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	84/436 (19%)
Slc38a5	XP_008771290.2	SLC5-6-like_sbd	56..466	CDD:382020	84/437 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352642
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940