Protein Alignment acs and unc-47

DIOPT Version :10

• Sequence 1: NP_647686.1
• Gene: acs / 38264
• FlyBaseID: FBgn0035300
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_499255.1
• Gene: unc-47 / 176431
• WormBaseID: WBGene00006783
• Length: 486
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 97/515 - (18%)
• Similarity: 192/515 - (37%)
• Gaps: 131/515 - (25%)

  Fly     2 NDDIKTVTVYPTTLELTTPTKSANGSN----DDYDPHQ-----------------------HREL 39
            |.::..|..|.     ..|....:|||    |..:|.|                       |.|.
 Worm    26 NQELNEVPSYQ-----NQPQTGESGSNPPPHDRLEPIQESVVSEQPQKDDINKQEEAKDDGHGEA 85

  Fly    40 KNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLH---ILIKCMYIL 101
            ..|.:..|...:...|..|..::.:|.|....|:.:   :..::| :|..|..   :||:|:|..
 Worm    86 SEPISALQAAWNVTNAIQGMFIVGLPIAVKVGGWWS---IGAMVG-VAYVCYWTGVLLIECLYEN 146

  Fly   102 CKRQRVPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQL-- 164
            ..::|..|...:.....|..:   |:     :|....:      ....|.:|:|..|:.::..
 Worm   147 GVKKRKTYREIADFYKPGFGK---WV-----LAAQLTE------LLSTCIIYLVLAADLLQSCFP 197

  Fly   165 -VDE--YLVVWDVRIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYIFEELPPL 226
             ||:  ::::....:..|..:..|.::      ..|:.|::.::  |:|...::||.:
 Worm   198 SVDKAGWMMITSASLLTCSFLDDLQIV------SRLSFFNAISH--LIVNLIMVLYCL------- 247

  Fly   227 SERDPFVA------------AGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGM 279
                .||:            ...|||..|.|:|...:...:..:|.||..|..|    .::....
 Worm   248 ----SFVSQWSFSTITFSLNINTLPTIVGMVVFGYTSHIFLPNLEGNMKNPAQF----NVMLKWS 304

  Fly   280 SIVLGLY-VLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYALQGYVTAHILW 343
            .|...:: |:.|..|:..:|..::..|:.::|...... :|.:...:...:||.|..|....:|.
 Worm   305 HIAAAVFKVVFGMLGFLTFGELTQEEISNSLPNQSFKI-LVNLILVVKALLSYPLPFYAAVQLLK 368

  Fly   344 DK----YLAKRF-------KETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILG 397
            :.    |....|       |..|:  :.:..|.|:||.|...|:::|.|...:.|||:...::|.
 Worm   369 NNLFLGYPQTPFTSCYSPDKSLRE--WAVTLRIILVLFTLFVALSVPYLVELMGLVGNITGTMLS 431

  Fly   398 LIFPVLLQICV----------QYTEGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILDII 447
            .|:|.|..:.:          ::.:|       :||....:|      :.|.|.|.::::
 Worm   432 FIWPALFHLYIKEKTLNNFEKRFDQG-------IIIMGCSVC------ISGVYFSSMELL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
acs	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:444915	85/443 (19%)
unc-47	NP_499255.1	Aa_trans	88..475	CDD:279788	85/443 (19%)