DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1139 and Slc38a1

DIOPT Version :9

Sequence 1:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_620187.1	Gene:	Slc38a1 / 170567	RGDID:	69645	Length:	485	Species:	Rattus norvegicus

Alignment Length:	518	Identity:	107/518 - (20%)
Similarity:	192/518 - (37%)	Gaps:	130/518 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 YPTTLELT-----TPTKSANGSNDDYDPHQHRELKNPTTNFQ-----------TFAHFLK----- 54
            :.:.||||     |..:..|.|||..|   ..|::|...|.:           |.:|..|
  Rat     4 FKSGLELTELQNMTVPEDDNVSNDSND---FTEVENGQINSKFISDRESRRSLTNSHLEKRKCDE 65

  Fly    55 -----------------ASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILC 102
                             |.:|:|:|.:..|.|:.|.:...:|...:..|::|.:::|     ::|
  Rat    66 YIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLL-----LIC 125

  Fly   103 KRQR--VPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFI----AESI 161
            .::.  :.|....:             :.........:.|..:..:.|....|:..:    ..:|
  Rat   126 SKETGCMVYEKLGE-------------QVFGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAI 177

  Fly   162 KQLV--DEYLVVW--DVRIHMCI----IIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYY 218
            |.|:  :|....|  |.|:.:.:    ||:||.|   :|||..|. ::|..:|..:|.|.|::.|
  Rat   178 KSLMGEEETFSAWYVDGRVLVVMVTFGIILPLCL---LKNLGYLG-YTSGFSLSCMVFFLIVVIY 238

  Fly   219 IFEELPPLS-ERDPFVAAG-------KLPTFFGTVLFALEAVGV-------ILAIEENMATPKSF 268
            ...::|.:: |::..|:|.       |..||....::||..:..       :|.|...: ..:|.
  Rat   239 KKFQIPCMNGEQNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSEL-KDRSQ 302

  Fly   269 VGPCGILNSGMSIVLGLYVLLGFFGY------------WKYGNESEGSI-TLNIPQSEIPAQVVK 320
            .....:.|.....:..:|.|...|||            .||  :|.|.| .|.:..:.|.|.::.
  Rat   303 KKMQMVSNISFFAMFVMYFLTAIFGYLTFYEKVQSDLLHKY--QSTGDILILTVRLAVIVAVILT 365

  Fly   321 V---FFAITTWISYALQGYVTAHILWDKYLAKRFKETRQTFYELIFRAIIVLLTFGCAVAIPDLS 382
            |   ||.:.:             .|::.....:|...|.....:|...||.||    .:.||.:.
  Rat   366 VPVLFFTVRS-------------SLFELAKKTKFHLCRHVLVTIILLVIINLL----VIFIPSMK 413

  Fly   383 VFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILD 445
            ....:||....::|..|.|..|.:  :.|...|....:.|...|.|..|:...::...:.|.|
  Rat   414 DIFGVVGVTSANMLIFILPSSLYL--KITNQDGDKNTQRIWAALFLALGVLFSLISIPLVIYD 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	88/445 (20%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	93/479 (19%)
Slc38a1	NP_620187.1	SLC5-6-like_sbd	69..472	CDD:382020	89/446 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352627
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750