Protein Alignment acs and SLC38A6

DIOPT Version :10

• Sequence 1: NP_647686.1
• Gene: acs / 38264
• FlyBaseID: FBgn0035300
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_001166173.1
• Gene: SLC38A6 / 145389
• HGNCID: 19863
• Length: 521
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 97/475 - (20%)
• Similarity: 176/475 - (37%)
• Gaps: 147/475 - (30%)

  Fly    36 HRELKNPTTNF-QTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMY 99
            ||: ::|..:| .:..:.:.|.:|:|:|.:....|:.|....:.|.|.:..||.|.:|:|:.
Human    38 HRQ-RSPGVSFGLSVFNLMNAIMGSGILGLAYVLANTGVFGFSFLLLTVALLASYSVHLLLS--- 98

  Fly   100 ILCKRQRVPYVSFSQAMNLGLKQGPPWLRCLAPIAVP---FVDGFLAFYHFGICCVYVVFIAESI 161
             :|.:..|  .|:.   :||          |....:|   .|.|.:...:.|....|::.|...:
Human    99 -MCIQTAV--TSYE---DLG----------LFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTEL 147

  Fly   162 KQLVDEYLV-----VW-----DVRIHMCI-IIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGII 215
            ...:.|:|.     .|     .:.|.:|: |:.||.|:..|..|    .::|:.:...::.|.::
Human   148 PAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFL----GYTSSLSFFFMMFFALV 208

  Fly   216 LYYIFEELP-PLSERDPFVAAG------------KLPTFFGTVLFALEAVGV-------ILAIEE 260
            :......:| ||:..  :|..|            ||..|.....:||..:..       ||.|..
Human   209 VIIKKWSIPCPLTLN--YVEKGFQISNVTDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPIYC 271

  Fly   261 NMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEG---------------------- 303
            .:.:| |......:.|:.:::...:|.:...|||..:.::.|.
Human   272 ELQSP-SKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLC 335

  Fly   304 ---SITLNIPQSEIPAQ--VVKVFFA--ITTWISYALQGYVTAHILWDKYLAKRFKETRQTFYEL 361
               ::.|.:|....||:  |..:||:  ..:||.:.|   :|                      |
Human   336 ILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFL---IT----------------------L 375

  Fly   362 IFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIK------ 420
            ....|||||    |:.:||:.....:||:...:.|..|||             |.|.:|
Human   376 ALNIIIVLL----AIYVPDIRNVFGVVGASTSTCLIFIFP-------------GLFYLKLSREDF 423

  Fly   421 --------LIINLLLLCFGI 432
                    ||::..|.|.|:
Human   424 LSWKKLGGLILSHRLACSGV 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
acs	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:444915	95/469 (20%)
SLC38A6	NP_001166173.1	SLC5-6-like_sbd	46..429	CDD:444915	89/450 (20%)