Protein Alignment acs and Slc38a1

DIOPT Version :10

• Sequence 1: NP_647686.1
• Gene: acs / 38264
• FlyBaseID: FBgn0035300
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_598847.2
• Gene: Slc38a1 / 105727
• MGIID: 2145895
• Length: 485
• Species: Mus musculus
• Alignment Length: 505
• Identity: 103/505 - (20%)
• Similarity: 196/505 - (38%)
• Gaps: 112/505 - (22%)

  Fly    11 YPTTLELT-----TPTKSANGSNDDYDPHQHRELKNPTTNFQ-----------TFAHFLK----- 54
            :.:.||||     |..:..|.|||..|   ..|::|...|.:           |.:|..|
Mouse     4 FKSGLELTELQNMTVPEDDNVSNDSND---FTEVENGQINSKFISDRESRRSLTNSHLEKRKCDE 65

  Fly    55 -----------------ASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILC 102
                             |.:|:|:|.:..|.|:.|.:...:|...:..|::|.:::|     ::|
Mouse    66 YIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLL-----LIC 125

  Fly   103 KRQR--VPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFI----AESI 161
            .::.  :.|....:             :.........:.|..:..:.|....|:..:    ..:|
Mouse   126 SKETGCMVYEKLGE-------------QVFGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAI 177

  Fly   162 KQLV--DEYLVVW--DVRIHMCI----IIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYY 218
            |.|:  ::....|  |.|:.:.:    ||:||.|   :|||..|. ::|..:|..::.|.|::.|
Mouse   178 KSLMGEEDAFSAWYVDGRVLVVMVTFGIILPLCL---LKNLGYLG-YTSGFSLSCMMFFLIVVIY 238

  Fly   219 IFEELPPLS-ERDPFVAAG-------KLPTFFGTVLFALEAVGV-------ILAIEENMATPKSF 268
            ...:.|.:| |::..|:|.       |..||....::||..:..       :|.|...: ..:|.
Mouse   239 KKFQTPCMSVEQNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSEL-KDRSQ 302

  Fly   269 VGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYAL 333
            .....:.|.....:..:|.|...|||..:..:.:..: |:..||.....::.|..|:...:
Mouse   303 KKMQMVSNISFFAMFVMYFLTAIFGYLTFYEKVQSDL-LHKYQSTGDILILTVRLAVIVAV---- 362

  Fly   334 QGYVTAHILWDKYLAKRFKETRQTFYEL---IFRAIIVLLTFGCAVA-IPDLSVFLSLVGSFCLS 394
              .:|..:|:....:..|:..::|.:.|   :...||:|:.....|. ||.:.....:||....:
Mouse   363 --ILTVPVLFFTVRSSLFELAKKTKFHLCRHVLVTIILLIIINLLVIFIPSMKDIFGVVGVTSAN 425

  Fly   395 ILGLIFPVLLQICVQYTEG-YGPFRIKLIINLLLLCFGIFGGVVGTYVSI 443
            :|..|.|..|.:.:...:| .|..||...:.|.|       ||:.:.:||
Mouse   426 MLIFILPSSLYLKITNQDGDKGTQRIWAALFLGL-------GVLFSLISI 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
acs	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:444915	91/469 (19%)
Slc38a1	NP_598847.2	SLC5-6-like_sbd	69..472	CDD:444915	87/437 (20%)