Protein Alignment mv and Nsmaf

DIOPT Version :10

• Sequence 1: NP_647681.2
• Gene: mv / 38259
• FlyBaseID: FBgn0288310
• Length: 3535
• Species: Drosophila melanogaster
• Sequence 2: NP_852054.2
• Gene: Nsmaf / 353233
• RGDID: 727868
• Length: 920
• Species: Rattus norvegicus
• Alignment Length: 981
• Identity: 246/981 - (25%)
• Similarity: 365/981 - (37%)
• Gaps: 279/981 - (28%)

  Fly  2503 EPIENLKPLCDALGIKENDSSWNLVHELDRLDQNRNNMAAKQK----TLLEKTVYRFEPLVQQCV 2563
            :||..: ||.|.|.|.::.            :...|...||.|    :|:...||..:
  Rat    72 QPILKI-PLRDCLKIGKHG------------ENGANKHFAKAKSLGISLIFSQVYFIK------- 116

  Fly  2564 ESSMVTTRKVAELQNAERKALMCHMKVYDDTYTYTKWLEIIRRMTHEGAPWHSAERAECSWELDD 2628
            |.::|...|:      ||..:           .|...||:..::...........||.|..:|.|
  Rat   117 EHNIVAPYKI------ERGKM-----------EYVFQLEVSGKVEDVVETLLQLHRASCLDKLGD 164

  Fly  2629 TEG--PSRVHTRLRRCHLDIDRRFFMNEYRPGQGHREDLEPYVRPLDYLIASYDQQLNISLNSQI 2691
            ...  .:.:.:||.|...|.:|                           ..|..::|::...:::
  Rat   165 QMAMITAILQSRLARTSFDKNR---------------------------FQSVSEKLHMECKAEM 202

  Fly  2692 LYNFAAKFLPVDGEIEGEIIITDLKLYFLATYRCRYFNVNCDIANITEIWLKRYQHQETAFEILL 2756
            :......        .|.:.|||..|||..........|...:.::..|:.:|:.......|:..
  Rat   203 VTPLVTN--------PGHVCITDTNLYFQPLNGYPKPVVQITLQDVRRIYKRRHGLMPLGLEVFC 259

  Fly  2757 DTNKSL-------FFSLQNADDWKIMREVFCDKIVATPDQSKVIAITQQWREGLLTNWEYLMTLN 2814
             |...|       |:..|:.||.......:.:..||   :....:...||:.|.|:|::||:.||
  Rat   260 -TEDDLCSDIYLKFYEPQDRDDLYFYIATYLEHHVA---EHTAESYMLQWQRGHLSNYQYLLHLN 320

  Fly  2815 QISGRTYNDLMQYPVFPWVLANYNSEVLDLREGHNFRRLGRPIAVQVEENEKHYISNYTYIDSTN 2879
            .::.|:.|||.||||||||:::|:|..|||.....||.|.:|:.....|..:..::.|..:....
  Rat   321 NLADRSCNDLSQYPVFPWVISDYSSPELDLSNPATFRDLSKPVGALNPERLERLLTRYQEMPEPK 385

  Fly  2880 TTMGSLILKPYHYSSHYSNSGTVLHFLVRVPPFTSYFLRYQDNDFDLPDRTFHALNTTWLLASRD 2944
                      :.|.||||:.|.||.:|||:.|  .|.|..|:..||..||.|:::..|| ....|
  Rat   386 ----------FMYGSHYSSPGYVLFYLVRIAP--EYMLCLQNGRFDNADRMFNSIAETW-KNCLD 437

  Fly  2945 SPTDVKELIPEFFCLPEMF-ENFERFKFGCRQNGERVEDVSLPPW--SQRDSRLFVLIHRQALES 3006
            ..||.|||||||:.....| .|..:...|.||.|:.|:||.||.|  |.:|   |:..::.||||
  Rat   438 GATDFKELIPEFYDEDASFLINSLKLDLGKRQGGQMVDDVELPAWASSPQD---FLQKNKDALES 499

  Fly  3007 ELVRNQIHNWIDLIFGYKQSGESAVEAINVFHPATYAVFLD-SEISDPIEREAVKTMVKTYGQMP 3070
            ..|...:|.||||||||||.|..|:.|.|||||.||...:| :.|.||.::.|:.|.:..:||.|
  Rat   500 SYVSEHLHEWIDLIFGYKQKGSEAIGAHNVFHPLTYEGGVDLNSIEDPDDKVAMLTQILEFGQTP 564

  Fly  3071 RQLFKSPHP---------ASKPLDY--SLVGKPIVSTVRGLRWGVYVGSP----------QLKAP 3114
            :|||.:|||         .|:...|  |:...|:              ||          :.|..
  Rat   565 KQLFVTPHPRRITPKFKSLSQASSYNASMTDSPV--------------SPGEESFEDLTEESKTL 615

  Fly  3115 SWAN-----------IHKIPGTEHLVSFCNTNVVYA----------------------------- 3139
            :|.|           |||...|...|| ||.:.|:.
  Rat   616 AWNNITKLQLHEQYKIHKEAVTGIAVS-CNGSSVFTTSQDSTLKMFSKESKMLQRSISFSNMALS 679

  Fly  3140 ----LPGRASVMQ--------------GAEPDTYNVISWGYDDRIVRIQPLNK------------ 3174
                |||..:|:.              |...||.    .|:||.:.:|...|.
  Rat   680 SCLLLPGDTTVISSSWDNNVYFYSIAFGRRQDTL----MGHDDAVSKICWHNDRLYSASWDSTVK 740

  Fly  3175 -----PQAKPKNLLHNGTFDDITACGCDVNSNQ---------LWFGHKSGRISVY---------- 3215
                 |...|....|.  ||.:.....||:.|.         |..|.|.|.::::
  Rat   741 VWSGVPAEMPGTKRHQ--FDLLAELEHDVSVNTINLNAVSTLLVSGTKEGLVNIWDLTTATLLHQ 803

  Fly  3216 -KCTGGLDSQQRASAKSRQSYARGFSLSYNSAFRKMTNKGIGGGGSERVDEAGNLHPTSSASSV- 3278
             .|..|.......|..||...:.|..                 |....:|....:..:|.||..
  Rat   804 ISCHSGTVCDAAFSPDSRHVLSTGVD-----------------GCLNVIDVQTGMLISSMASEEP 851

  Fly  3279 ------NSSSISSGGDAFQRDGADLNW--LGPTLLVR---HTDEITCITLSVEFKIAVTAGRDGI 3332
                  :.:|:.||    .|.|..|.|  ||..:..|   ||..:|||.::.:....:|.|.|..
  Rat   852 QRCFVWDGNSVLSG----SRTGELLVWDLLGAKVSERIQGHTGAVTCIWMNEQCSSIITGGEDRQ 912

  Fly  3333 AVIWDL 3338
            .:.|.|
  Rat   913 VMFWKL 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mv	NP_647681.2	PH-like	2704..2785	CDD:473070	17/87 (20%)
		Beach	2796..3080	CDD:214982	120/296 (41%)
		WD40	<3302..>3518	CDD:441893	11/40 (28%)
Nsmaf	NP_852054.2	PH-like	192..285	CDD:473070	18/101 (18%)
		Beach	304..575	CDD:460459	120/286 (42%)
		WD40	<624..919	CDD:441893	64/323 (20%)
		WD40 repeat	636..673	CDD:293791	6/37 (16%)
		WD40 repeat	679..715	CDD:293791	7/39 (18%)
		WD40 repeat	720..764	CDD:293791	7/45 (16%)
		WD40 repeat	770..805	CDD:293791	5/34 (15%)
		WD40 repeat	811..848	CDD:293791	7/53 (13%)
		WD40 repeat	892..916	CDD:293791	6/23 (26%)