Protein Alignment mv and Wdr81

DIOPT Version :10

• Sequence 1: NP_647681.2
• Gene: mv / 38259
• FlyBaseID: FBgn0288310
• Length: 3535
• Species: Drosophila melanogaster
• Sequence 2: XP_038941944.1
• Gene: Wdr81 / 303312
• RGDID: 1311334
• Length: 1944
• Species: Rattus norvegicus
• Alignment Length: 743
• Identity: 163/743 - (21%)
• Similarity: 269/743 - (36%)
• Gaps: 177/743 - (23%)

  Fly  2476 DEFQRAIICDAKMIKALL---WLSLLEDMPEPIENLKPLCDALGIKENDSSWNLVHELDRLDQ-- 2535
            |..|.|:......:.||:   ||:.|.:     ..|.|...|.|:.|.:....|...:.||.|
  Rat    41 DARQLALAPGGTHVVALVSTRWLASLRE-----RRLGPCPRAEGLGEAEVRTLLQRSVQRLPQGW 100

  Fly  2536 NRNNMAAKQKTLLEKTVYRFEPLVQ-QCVESSMVTTRKVAELQNAERKALMCH-MKVYDDTYTYT 2598
            .|..:...:|..|...:.|..|..: .|  |....||.:.|:.....:.|..| ...|...|:::
  Rat   101 TRVEVHGLRKRRLSYPLSRVLPFEEGSC--SPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHS 163

  Fly  2599 ------KWLEIIRRMTHE--GAPW-HSAERAECSWELDDTEGPSRVHT---RLRRCH--LDIDRR 2649
                  ..|:.||:....  |..: ...|..:|...:.|  ||||..:   .|.|..  |:....
  Rat   164 TAPSAIPALDSIRQALQRVYGCTFLPVGESMQCLSNVRD--GPSRGSSACPSLLRAEALLESPEM 226

  Fly  2650 FFMNEYRPGQGHREDLEPYVRPLDYLIASYDQQLNISLNSQILYNFAAKFLPVDGEIEGEIIITD 2714
            .::            :.|||:              .||:..:.::.|            ::..:.
  Rat   227 LYV------------VHPYVQ--------------FSLHDVVTFSPA------------KLTNSQ 253

  Fly  2715 LKLYFL------ATYRCRYFNVNCDIANITEIWLKRYQHQETAFEILLDTNKSLFFSLQNADDWK 2773
            .|:.|:      |...|....:.|...::..|.:    .::...|:.||.:.   :.:.:.|:
  Rat   254 AKVLFILFRVLRAMDACHRQGLACGALSLHHIAV----DEKLCSELRLDLSA---YEMPSEDE-- 309

  Fly  2774 IMREVFCDK----IVATPD----------QSKVIAITQQWREGLLTNWEYLMTLNQISGRTYNDL 2824
             .:||..:|    :.:..|          |.::..:...|..|.::|:.|||.||:::||...|.
  Rat   310 -NQEVSEEKDRTGVKSEKDGEGRPGCPTCQKELRGLVLDWVHGRVSNFYYLMQLNRLAGRRQGDP 373

  Fly  2825 MQYPVFPWVLANYNSEVLDLREGH-NFRRLGRPIAVQVEENEKHYISNYTYIDSTNTTMGSLILK 2888
            ..:||.||        |:|....: .||.| |....::.:.:|.....|..........|:...:
  Rat   374 NYHPVLPW--------VVDFTTPYGRFRDL-RKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGSGE 429

  Fly  2889 PYHYSSHYSNSGTVLHFLV----RVP-PFTSYFLRYQDNDFDLPDRTFHALNTTWLLASRDSPTD 2948
            |.|...|.|:..:.:.:.|    |.| ......:|.|....:.| .|...:. ||      :|
  Rat   430 PLHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYP-ATMERMQ-TW------TP-- 484

  Fly  2949 VKELIPEFFCLPEMFENFERFKFGCRQNGERVEDVSLPPWSQRDSRLFVLIHRQALESELVRNQI 3013
             .|.||||:..|.:|         |..:.: :.|:.:|.|...:.. ||..||..|||..|...:
  Rat   485 -DECIPEFYTDPSIF---------CSIHPD-MPDLDVPAWCSSNQE-FVTAHRALLESWEVSQDL 537

  Fly  3014 HNWIDLIFGYKQSGESAVEAINV-FHPATYAVFLDSEISDPIEREAVKTMVKTYGQMPRQLFKSP 3077
            |:||||.||||..|:.||:..|| .|      .:|:.           |.:.:||.:  |||..|
  Rat   538 HHWIDLTFGYKLQGKEAVKEKNVCLH------LVDAH-----------THLTSYGVV--QLFDQP 583

  Fly  3078 HP----------ASKPLDYSLVGKPIVST----------VRGLRWGVYVGSPQLKAPSWANIHKI 3122
            ||          ...||...|:.:||...          :.|.  |.:|.........|......
  Rat   584 HPQRLAGAPALAPEPPLIPRLLVQPIQEATGQEDISGQLINGA--GRHVVEVTPCESGWTRERPT 646

  Fly  3123 PGTEHLVSFCNTNVVYALPGRASVMQGA 3150
            .|.:.|..........::||:|....|:
  Rat   647 AGEDDLEQATEALDSISIPGKAGDQPGS 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mv	NP_647681.2	PH-like	2704..2785	CDD:473070	13/90 (14%)
		Beach	2796..3080	CDD:214982	82/300 (27%)
		WD40	<3302..>3518	CDD:441893
Wdr81	XP_038941944.1	Beach	347..587	CDD:100117	82/289 (28%)
		WD40	<1643..1942	CDD:441893
		WD40 repeat	1655..1698	CDD:293791
		WD40 repeat	1703..1737	CDD:293791
		WD40 repeat	1746..1782	CDD:293791
		WD40 repeat	1792..1825	CDD:293791
		WD40 repeat	1834..1867	CDD:293791
		WD40 repeat	1874..1896	CDD:293791