Protein Alignment Kcnf1 and Shawl

DIOPT Version :9

• Sequence 1: NP_963289.2
• Gene: Kcnf1 / 382571
• MGIID: 2687399
• Length: 505
• Species: Mus musculus
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 608
• Identity: 170/608 - (27%)
• Similarity: 248/608 - (40%)
• Gaps: 173/608 - (28%)

Mouse    32 GEDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 96
            ||: .|::||.|:|...|...|.:.|.|||:.|...||           :|||...|::|||.|.
  Fly     3 GEN-RIILNVSGIRYETYKATLKKIPATRLSRLTEALA-----------NYDPVLNEYFFDRHPG 55

Mouse    97 AFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLIL 161
            .|..::..|..|::|....:|...|:.|::||.:|...::.||.|..|..|:....:|     ||
  Fly    56 VFTQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLA-----IL 115

Mouse   162 DDLGVD------------------AAEGR---WRRCQKCVWKFLEKPESSCPARVVAVLSFLLIL 205
            |.|.::                  .:.|.   |:|.:..:|...::|.||..|::||.:|...|.
  Fly   116 DKLDIENEKPTEEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIF 180

Mouse   206 VSSVVMCMGTIPELQVVD----------------------------------------------- 223
            ||.:..|:.|.|..: ||
  Fly   181 VSVISFCLKTHPGFR-VDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPT 244

Mouse   224 ---------SEGN-------------------------------------------RVEHPTLEN 236
                     |.||                                           |.:|..:|.
  Fly   245 FRVTNYTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIET 309

Mouse   237 ----------VETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARM 291
                      ||..|..||.:|.::||..|||...|..|.:||:|..|.|.||     |.:..||
  Fly   310 YGQPHEAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY-----TDVMQRM 369

Mouse   292 MELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYT 356
            .|.|.:   ::|..|:||.|:|||.|||.||:.|.:..|.|.|||.||:.:|.:||..|::|.|.
  Fly   370 GEYTGL---LEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYY 431

Mouse   357 ME--QSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIIN 419
            .|  |.:|:..|||||...||||:|||||||||:.|||..|....|:..|.||:.||||:..|::
  Fly   432 AEKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVS 496

Mouse   420 NFVRYYNKQRVLETAAKHELELMELNSSSAEGKP----GGSRSDLDTLPPE----------PAAR 470
            ||..:|:..:......|....::.:.....:.:|    .|..:.:...||.          |...
  Fly   497 NFSMFYSHTQARSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQTPPTGPGLVAGGVVPVGA 561

Mouse   471 EGPSWGSRLKLSHSDTFIPLLTE 493
            .||..|.. .:.||....|:..:
  Fly   562 GGPGLGGH-AVGHSAAGAPMFKD 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcnf1	NP_963289.2	BTB_POZ_Kv5_KCNF1	35..150	CDD:349690	37/114 (32%)
		Ion_trans	193..429	CDD:366146	107/346 (31%)
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	33/102 (32%)
		BTB_2	7..97	CDD:280393	32/100 (32%)
		Ion_trans	307..506	CDD:278921	90/206 (44%)
		Ion_trans_2	<449..499	CDD:285168	27/49 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331021at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910