DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mfap1 and Mfap1a

DIOPT Version :9

Sequence 1:	NP_647679.1	Gene:	Mfap1 / 38256	FlyBaseID:	FBgn0035294	Length:	478	Species:	Drosophila melanogaster
Sequence 2:	NP_001178893.1	Gene:	Mfap1a / 499878	RGDID:	1562232	Length:	439	Species:	Rattus norvegicus

Alignment Length:	478	Identity:	268/478 - (56%)
Similarity:	339/478 - (70%)	Gaps:	44/478 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAATAAAAASGIQSTAGAIPMRNEKGELSMQKVKVQRYISGKRPDYARADSSSEESDDDDFIDT 65
            ||..:|......|||||||:|:||||||:||:||||:||:||||||||..:||.||.::..||..
  Rat     1 MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKK 65

  Fly    66 RKRLERHKAERHKLELSRQGGSAEGEERAAGEGQEEDDAEVDDPRLRRLRQRPVDMEDMERERRE 130
            .|                       |:.|..|.||||.:  .|||||||:.|  ..||:| ||..
  Rat    66 AK-----------------------EQEAEPEEQEEDSS--SDPRLRRLQNR--ISEDVE-ERLA 102

  Fly   131 RHRHIHEPEIM-ESDSEDEEEDEGAQGAIQRGTNKITLASESDTDAELSDTELENRRTKLRSRML 194
            |||.|.|||:: ||||    |.||....::|..      |..:.:.|:.|.|:|.||..:|.|..
  Rat   103 RHRKIVEPEVVGESDS----EVEGDAWRLERED------SSEEEEEEIDDEEIERRRGMMRQRAQ 157

  Fly   195 QQQREE-EVLQKEDEKQS-ESSESESSEYEEETESEEDNEPRLKPLFVRKRDRATIQEKEREAQK 257
            :::.|| ||::.|||.:| |.|||| |||||.|:||::.||||||:|:||:||.|:||:|.||.:
  Rat   158 ERKNEEMEVMEVEDEGRSGEESESE-SEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALR 221

  Fly   258 QKQLEAEAKRAAKERRRATLRMVEESVKKDLEKTKPETNEACIEDVCTDDENDEVEYEAWKLREL 322
            ||:||.||||.|:|||:.||::|||..||:||:.|  .:.|.::.:.|||||||.||||||:|||
  Rat   222 QKELEQEAKRMAEERRKYTLKIVEEETKKELEENK--RSLAALDALNTDDENDEEEYEAWKVREL 284

  Fly   323 KRMKRDREERDNVEREKLDIDRMRNMTEEERRQELRQNPKVVTNKATKGKYKFLQKYYHRGAFYL 387
            ||:|||||:|:.:|:||.:|:||||:||||||.|||.|.||:||||.||||||||||||||||::
  Rat   285 KRIKRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFM 349

  Fly   388 DEENDVLKRDFAQATLEDHFDKTILPKVMQVKNFGRCGRTKYTHLVDQDTTKFDSPWYAESSSNI 452
            ||:.:|.||||:..||||||:|||||||||||||||.||||||||||||||.|||.|..||:.|.
  Rat   350 DEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNT 414

  Fly   453 KFHNEHAGGMRQQFDKPTGSKRK 475
            ||..:.|.|:|..|::|:..|||
  Rat   415 KFFKQKAAGVRDVFERPSAKKRK 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mfap1	NP_647679.1	MFAP1	233..437	CDD:284422	142/203 (70%)
Mfap1a	NP_001178893.1	MFAP1	197..399	CDD:284422	142/203 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1425
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4332
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1535406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870