Protein Alignment CG5687 and SLC5A6

DIOPT Version :10

• Sequence 1: NP_647678.3
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_066918.2
• Gene: SLC5A6 / 8884
• HGNCID: 11041
• Length: 635
• Species: Homo sapiens
• Alignment Length: 578
• Identity: 185/578 - (32%)
• Similarity: 312/578 - (53%)
• Gaps: 36/578 - (6%)

  Fly    78 IPASAELEECSAPS-HKATFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGS-EMSIF 140
            :..||.|...|..| ..:|||..|||:.:.:||:||.||:::.....|..:..|.|:.. :|...
Human     5 VSTSAPLSPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCL 69

  Fly   141 PVTLSLTTSFITAIELLGNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLG 205
            ||.|||..:|.:|:.:||.|||:|..|||:..:.....:.:.:...||.|:::::.|||.||||.
Human    70 PVALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLE 134

  Fly   206 IRFGKEIRILGAVLYVIQMCFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAV 270
            :||.|.:|:.|.|.::.||..|..|.:.||::||:..||.|..::|:.:.:||..|::.||:|||
Human   135 LRFNKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAV 199

  Fly   271 VIADSFQAAVLAVSLVLIVGLGCFYSGNPIQVFQTASDHNRLEFFNMDPDPTTRHTVWSVVIGGF 335
            :..|.||..|:.:..:.::.:|....|...:|:..||.|.|:..|.:||||..|||.|::..||.
Human   200 IWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFGGV 264

  Fly   336 FYWTSLFCTNQASVQKCMSLKSLRLAKIA----LGFAIIGLIVVFLLNFYTGLMVFTHYADCDPL 396
            |...||:..|||.||:.:|.::.:.|.::    ..|..:.|.|..|:    ||::|.:|.:....
Human   265 FMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLI----GLVMFAYYQEYPMS 325

  Fly   397 TAGRISATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIK 461
            .....:|.||.:.|:|::..:.:..:.|:|:|.:|:.||.|::||.|||:.||.|| |:.....:
Human   326 IQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMED-LIRPWFPE 389

  Fly   462 ISPEKGATYAKWMSLGFGIASFGLVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTK 526
            .|..:....::.::.|:|:...|:.:|...:|.||||.:::.|::||..||||.||:....||..
Human   390 FSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPP 454

  Fly   527 GAFYGGLLSLALVIFVGVVAQIVSV--EQPALPTSIDKCDCHVNMTNIIGSLLT-EPLEVIEEGG 588
            ||..|.|..|.:..::|:.:.:.|:  ..|..|::........|:|  :.::.| .||...
Human   455 GAVVGLLAGLVMAFWIGIGSIVTSMGSSMPPSPSNGSSFSLPTNLT--VATVTTLMPLTTF---- 513

  Fly   589 FTSWP-----IFRLSYMWYSMIGCLLTVFLGWFISLIIDFIQRRNVLKITGKDIDNPA 641
              |.|     .:.|||:|||.......:.:|..:||:...::.|::         |||
Human   514 --SKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSL---------NPA 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_647678.3	SLC5sbd_NIS-SMVT	99..620	CDD:271383	172/533 (32%)
SLC5A6	NP_066918.2	SLC5sbd_SMVT	24..550	CDD:271394	175/538 (33%)