Protein Alignment CG5687 and SLC5A4

DIOPT Version :10

• Sequence 1: NP_647678.3
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: XP_016884409.1
• Gene: SLC5A4 / 6527
• HGNCID: 11039
• Length: 689
• Species: Homo sapiens
• Alignment Length: 555
• Identity: 126/555 - (22%)
• Similarity: 231/555 - (41%)
• Gaps: 124/555 - (22%)

  Fly   125 GSSSNEFLLGSEMSIFPVTLSLTTSFITAIELLG--------NPSEMYFQGTQFVLIVIPMVIVI 181
            |:....||.|.:|:.:|:..||..|.|.:...:|        ..:.:.|:.|..|:::|
Human    83 GTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLI------ 141

  Fly   182 PVAVKIFYPIYFKMELTSCYEYLGIRFGKE-----IRILGAVLYVIQMCFYTAVAVLAPAIALSK 241
              ...||.|||.|..:.:..|||..|||.|     :.||...:.|:.:   .:..:.|.||.:..
Human   142 --LGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLL---ISADIFAGAIFIKL 201

  Fly   242 ATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLVLIVG-----LGCFYS----- 296
            |.|||..:|:.::..:...|::.||:.:|:..|:.|..::.:...:::|     :|.:.|
Human   202 ALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKY 266

  Fly   297 ---------GNPIQVFQTASDHN-RLEFFNMDPDPTTRHTVWSVVIGG-----FFYWTSLFCTNQ 346
                     |:.:.:  :||.:. |.:.|::..|..|....|..:|.|     .:||    ||||
Human   267 VNATPSVVEGDNLTI--SASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYW----CTNQ 325

  Fly   347 ASVQKCMSLKSLRLAKIA-LGFAIIGLIVVFLL--------NFYTGLMVFTHYADCDPLTAGRIS 402
            ..||:|:..|.:...|.| :..|.:.|:.:||:        ..||.::.....::|.......:.
Human   326 VIVQRCLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVG 390

  Fly   403 ATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKG 467
            .|:...|..|:....  ..:.|:.::.:.|:.:.::.|..||.|.:...||.....  |.:.||.
Human   391 CTNYAYPTMVLELMP--QGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMR--KQASEKE 451

  Fly   468 ATYAKWMSLGFGIASFGLVFI---------------VEHLGGVLQATLTLNGLIGGVTLGLFVLG 517
            ...|            |.:|:               |...|.::..|.:::..:|.....:|||.
Human   452 LLIA------------GRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLA 504

  Fly   518 IACKQANTKGAFYGGLLSLALVIFVGVVAQIVSVEQPA----LPTSIDKCDCHV----------- 567
            |.||:.|.:|||:|.::.||:    |::..|.......    .|::..|..|.|
Human   505 IFCKRVNEQGAFWGLMVGLAM----GLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFF 565

  Fly   568 -NMTNIIG-SLLTEPLEVIEEGGFTSWPIFRLSYM 600
             :|...:| ||||:|:..:.        ::||.::
Human   566 GSMLVTLGISLLTKPIPDVH--------LYRLCWV 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_647678.3	SLC5sbd_NIS-SMVT	99..620	CDD:271383	126/555 (23%)
SLC5A4	XP_016884409.1	SLC5-6-like_sbd	76..689	CDD:444915	126/555 (23%)