Protein Alignment CG5687 and SLC5A1

DIOPT Version :9

• Sequence 1: NP_001286910.1
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_000334.1
• Gene: SLC5A1 / 6523
• HGNCID: 11036
• Length: 664
• Species: Homo sapiens
• Alignment Length: 584
• Identity: 133/584 - (22%)
• Similarity: 243/584 - (41%)
• Gaps: 116/584 - (19%)

  Fly    91 SHKATFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGSEMSIFPVTLSLTTSFI---- 151
            :|:...:..|..|::...|:.:.:|::..|....|:....||.|..|..:|:..||..|.|
Human    19 THELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGH 83

  Fly   152 -TAIELLGNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRFGKE---- 211
             ..:...|..|.:...|.::..:|:.:|:     ..:|.|||.|..:.:..|||..|||.:
Human    84 FVGLAGTGAASGIAIGGFEWNALVLVVVL-----GWLFVPIYIKAGVVTMPEYLRKRFGGQRIQV 143

  Fly   212 -IRILGAVLYVIQMCFYTAVA--VLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIA 273
             :.:|..:||:     :|.::  :.:.||.::.|.||:..:|:.|:..:...|:..||:.||:..
Human   144 YLSLLSLLLYI-----FTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYT 203

  Fly   274 DSFQAAVLAVSLVLIVGLGCFYSGNPIQVFQ---------TASDHN----------RLEFFNMDP 319
            |:.|..::.|..:::.|. .|:.......|.         ..||.|          |.:.|::..
Human   204 DTLQTVIMLVGSLILTGF-AFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFHIFR 267

  Fly   320 DPTTRHTVWSVVIGG-----FFYWTSLFCTNQASVQKCMSLKSLRLAK---IALGFAIIGLIVVF 376
            ||.|....|...|.|     .:||    ||:|..||:|:|.|::...|   |..|:  :.|:.:|
Human   268 DPLTGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGY--LKLMPMF 326

  Fly   377 LL--------NFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVINTYEHISSVAGIFVAGIFAA 433
            ::        ..||..:.....::|:.....::..|:...|..|:....  :.:.|:.::.:.|:
Human   327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMP--NGLRGLMLSVMLAS 389

  Fly   434 SLGTVASALNSLSAVTCEDLLVNGMNIKISPEKGATYAKWMSLG-------FGIASFGLVFIVE- 490
            .:.::.|..||.|.:..       |:|.....|.|:..:.|..|       .|| |...|.||:
Human   390 LMSSLTSIFNSASTLFT-------MDIYAKVRKRASEKELMIAGRLFILVLIGI-SIAWVPIVQS 446

  Fly   491 -HLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVGVVAQIVS---- 550
             ..|.:.....::...:|.....:|:|.|..|:.|..|||:|    |.|.:.:|:...|..
Human   447 AQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWG----LILGLLIGISRMITEFAYG 507

  Fly   551 ----VEQPALPTSIDKCDCHV-----------NMTNIIGSLLTEPLEVIEEGGFTSWPIFRLSY 599
                :|....||.|  |..|.           .:|.::.||||:|:..:.        ::||.:
Human   508 TGSCMEPSNCPTII--CGVHYLYFAIILFAISFITIVVISLLTKPIPDVH--------LYRLCW 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	132/576 (23%)
SLC5A1	NP_000334.1	SLC5sbd_SGLT1	27..664	CDD:271379	132/576 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810